Trial Outcomes & Findings for Adolescent and Child Suicide Prevention in Routine Clinical Encounters (NCT NCT04844021)

NCT ID: NCT04844021

Last Updated: 2024-07-25

Results Overview

Reach is the proportion of eligible well-child visits who received the S.A.F.E. Firearm program. "Participants" refers to well-child visits. For each well-child visit, data regarding S.A.F.E. Firearm delivery were available in the form of binary indicators, with 1 indicating S.A.F.E. Firearm was delivered during the visit and 0 indicating S.A.F.E. Firearm was not delivered during the visit. Reach outcomes presented below are means of the binary indicators, which were calculated across all eligible well-child visits.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

47307 participants

Primary outcome timeframe

EHR data on reach will be extracted for the time period: the beginning of the active implementation period through the end of the active implementation period (12 months total)

Results posted on

2024-07-25

Participant Flow

We included children (ages 5-17) attending an in-person well-child visit at a participating pediatric clinic from March 14, 2022 until March 20, 2023. Demographic information and outcomes were assessed for all eligible visits during the study period (e.g., demographic information for two well-child visits with the same patient are included as two separate "participants" in our demographic descriptive statistics). Data were extracted from the electronic health record (EHR).

Randomization was at clinic level. Clinics and all clinicians at them received Nudge or Nudge+. Clinics and clinicians are NOT considered "enrolled participants" in our primary outcomes analysis. Parents attending visits with the child received S.A.F.E. Firearm from clinicians, but are NOT considered "enrolled participants" in our primary outcomes analysis. Units of analysis for the primary outcome are number of visits; thus, "participants" in this participant flow refers to well-child visits.

Unit of analysis: clinics

Participant milestones

Participant milestones
Measure
Nudge
Clinics randomized to the Nudge condition will receive the EHR prompt only. The investigators will add default language to the standard Well Child Visit workflow to serve as a reminder and allow for tracking of S.A.F.E. Firearm implementation. The clinician will be asked to denote whether the program was delivered (e.g., whether conversation around firearm storage was conducted, whether cable firearm lock was offered) to the parent during the visit.
Nudge+
This arm consists of Nudge as described, as well as facilitation. Facilitation (i.e., external support delivered by health system employees not employed within the clinic site) will be offered for 12 months to each clinic, in keeping with other implementation trials. The role of the facilitator is to engage with study clinics, to assist each clinic in setting change and performance goals around the implementation of S.A.F.E. Firearm, and to troubleshoot implementation barriers.
Overall Study
STARTED
24989 15
22318 15
Overall Study
COMPLETED
24989 15
22318 14
Overall Study
NOT COMPLETED
0 0
0 1

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Adolescent and Child Suicide Prevention in Routine Clinical Encounters

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Nudge
n=24989 Participants
Clinics randomized to the Nudge condition will receive the EHR prompt only. The investigators will add default language to the standard Well Child Visit workflow to serve as a reminder and allow for tracking of S.A.F.E. Firearm implementation. The clinician will be asked to denote whether the program was delivered (e.g., whether conversation around firearm storage was conducted, whether cable firearm lock was offered) to the parent during the visit.
Nudge+
n=22318 Participants
This arm consists of Nudge as described, as well as facilitation. Facilitation (i.e., external support delivered by health system employees not employed within the clinic site) will be offered for 12 months to each clinic, in keeping with other implementation trials. The role of the facilitator is to engage with study clinics, to assist each clinic in setting change and performance goals around the implementation of S.A.F.E. Firearm, and to troubleshoot implementation barriers.
Total
n=47307 Participants
Total of all reporting groups
Age, Continuous
11.122 years
STANDARD_DEVIATION 3.718 • n=5 Participants
11.448 years
STANDARD_DEVIATION 3.703 • n=7 Participants
11.276 years
STANDARD_DEVIATION 3.714 • n=5 Participants
Sex/Gender, Customized
Sex · female
12143 Participants
n=5 Participants
10948 Participants
n=7 Participants
23091 Participants
n=5 Participants
Sex/Gender, Customized
Sex · male
12843 Participants
n=5 Participants
11367 Participants
n=7 Participants
24210 Participants
n=5 Participants
Sex/Gender, Customized
Sex · unknown
3 Participants
n=5 Participants
3 Participants
n=7 Participants
6 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
2459 Participants
n=5 Participants
3879 Participants
n=7 Participants
6338 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
19966 Participants
n=5 Participants
16580 Participants
n=7 Participants
36546 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
2564 Participants
n=5 Participants
1859 Participants
n=7 Participants
4423 Participants
n=5 Participants
Race/Ethnicity, Customized
Patient race · White
10741 Participants
n=5 Participants
11181 Participants
n=7 Participants
21922 Participants
n=5 Participants
Race/Ethnicity, Customized
Patient race · Black or African American
7013 Participants
n=5 Participants
3438 Participants
n=7 Participants
10451 Participants
n=5 Participants
Race/Ethnicity, Customized
Patient race · Asian
1154 Participants
n=5 Participants
1348 Participants
n=7 Participants
2502 Participants
n=5 Participants
Race/Ethnicity, Customized
Patient race · Native American or Alaska Native
94 Participants
n=5 Participants
79 Participants
n=7 Participants
173 Participants
n=5 Participants
Race/Ethnicity, Customized
Patient race · Native Hawaiian or Other Pacific Islander
33 Participants
n=5 Participants
49 Participants
n=7 Participants
82 Participants
n=5 Participants
Race/Ethnicity, Customized
Patient race · Other race
1471 Participants
n=5 Participants
1210 Participants
n=7 Participants
2681 Participants
n=5 Participants
Race/Ethnicity, Customized
Patient race · More than one race
781 Participants
n=5 Participants
937 Participants
n=7 Participants
1718 Participants
n=5 Participants
Race/Ethnicity, Customized
Patient race · Unknown
3702 Participants
n=5 Participants
4076 Participants
n=7 Participants
7778 Participants
n=5 Participants

PRIMARY outcome

Timeframe: EHR data on reach will be extracted for the time period: the beginning of the active implementation period through the end of the active implementation period (12 months total)

Population: "Participants" refers to well-child visits with patients ages 5-17. Data were extracted from the electronic health record (EHR).

Reach is the proportion of eligible well-child visits who received the S.A.F.E. Firearm program. "Participants" refers to well-child visits. For each well-child visit, data regarding S.A.F.E. Firearm delivery were available in the form of binary indicators, with 1 indicating S.A.F.E. Firearm was delivered during the visit and 0 indicating S.A.F.E. Firearm was not delivered during the visit. Reach outcomes presented below are means of the binary indicators, which were calculated across all eligible well-child visits.

Outcome measures

Outcome measures
Measure
Nudge
n=24989 Participants
Clinics randomized to the Nudge condition will receive the EHR prompt only. The investigators will add default language to the standard Well Child Visit workflow to serve as a reminder and allow for tracking of S.A.F.E. Firearm implementation. The clinician will be asked to denote whether the program was delivered (e.g., whether conversation around firearm storage was conducted, whether cable firearm lock was offered) to the parent during the visit.
Nudge+
n=22318 Participants
This arm consists of Nudge as described, as well as facilitation. Facilitation (i.e., external support delivered by health system employees not employed within the clinic site) will be offered for 12 months to each clinic, in keeping with other implementation trials. The role of the facilitator is to engage with study clinics, to assist each clinic in setting change and performance goals around the implementation of S.A.F.E. Firearm, and to troubleshoot implementation barriers.
Reach
0.2735 proportion of visits
Interval 0.268 to 0.279
0.4045 proportion of visits
Interval 0.3981 to 0.4109

SECONDARY outcome

Timeframe: surveys collected from parents within two weeks of well-child visit. Surveys will be collected during the duration of the pre-implementation, active implementation, and sustainment phases (30 months total)

Whether the clinician followed the two S.A.F.E. Firearm steps (counseling and offering cable lock), measured via parent-report

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Parent surveys will be collected from parents within two weeks of well-child visit from pre-implementation through sustainment (30 months total)

Parent-report of acceptability of the S.A.F.E. Firearm program. Parents will be asked to answer questions pertaining to the acceptability of program components. Specifically, they will answer yes/no questions developed by the research team which ask whether they found the component acceptable.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Clinician surveys will be collected at two time points during the study period: during pre-implementation (surveys will be administered for approximately 1 month) and during active implementation (surveys will be administered for approximately 1 month)

Clinician-report of acceptability of the S.A.F.E. Firearm program. Acceptability of the implementation strategies - EHR nudge and facilitation - will be collected from clinicians as well. Clinicians will be asked questions developed by the research team about whether they found various components of the program and implementation strategies acceptable, and will answer each question with a Likert-scaled answer.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Cost data will be collected from pre-implementation through sustainment (30 months total)

Cost of the implementation strategies (EHR nudge, facilitation) and the S.A.F.E. Firearm program delivery. Data on the cost of implementing the program (e.g., costs for printing program materials and distributing firearm locks) and the implementation strategies (e.g., facilitator full-time equivalent \[FTE\] time) will be collected to estimate the overall cost of the program and implementation strategy delivery.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Cable lock distribution data will be collected from active implementation through sustainment (24 months total)

Number of cable locks distributed by each clinic will be collected

Outcome measures

Outcome data not reported

Adverse Events

Nudge

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Nudge+

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr. Rinad Beidas

Northwestern University

Phone: 312-503-0546

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place