Comparison of the Decannulation Protocol With Suctioning and Capping in Severe Acquired Brain Injury Patients

NCT ID: NCT04835272

Last Updated: 2021-10-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

104 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-11-01

Study Completion Date

2023-10-30

Brief Summary

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Single-center randomized trail focused on tracheostomized patients with severe acquired brain injury , comparing two different decannulation protocols:

1. an assessment of readiness for decannulation that was based on suctioning frequency
2. an assessment that was based on tracheostomy capping

Detailed Description

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Conditions

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Tracheostomy Decannulation Acquired Brain Injury

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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control group

In the control group, the decision to decannulate was based on a 48-hour capping trial.

Group Type NO_INTERVENTION

No interventions assigned to this group

intervention group

In the intervention group, the decision to decannulate was based on suctioning frequency.

Group Type EXPERIMENTAL

the Decannulation Protocol With Suctioning

Intervention Type PROCEDURE

In the intervention group, the decision to decannulate was based on suctioning frequency. Patients underwent decannulation when they had had no more than two aspirations every 8 hours during during a 24-hour period. Patients in this group did not undergo capping trials.

Interventions

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the Decannulation Protocol With Suctioning

In the intervention group, the decision to decannulate was based on suctioning frequency. Patients underwent decannulation when they had had no more than two aspirations every 8 hours during during a 24-hour period. Patients in this group did not undergo capping trials.

Intervention Type PROCEDURE

Other Intervention Names

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the Decannulation Protocol With Capping

Eligibility Criteria

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Inclusion Criteria

* Within three months of onset
* Age≥18 years old
* GCS≥8
* Clinical stability( defined as the absence of fever, sepsis, or active infection and hemodynamic stability)
* Without massive pooling or silent aspiration of saliva, more than one efficient swallow per minute, adequate cough reflex were tested by gently touching the aryepiglottic region with the tip of the endoscope.
* Passing a tracheostomy-tube de-cuff test(de-cuff the tube for 3 days without pulmonary complications.
* Without significant airway stenosis.

Exclusion Criteria

* Patients with pending diagnostic or therapeutic procedures and were considered by the clinicians to be at risk for neurologic deterioration
* Medical history of severe respiratory system or heart disease
* Neuromuscular disease other than ICU-acquired weakness, or tracheostomy for airway control
* Don't get informed consent from patient or guardian
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Fu Xing Hospital, Capital Medical University

OTHER

Sponsor Role lead

Responsible Party

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Song Lu

Attending doctor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Yong Wang

Role: STUDY_CHAIR

Rehabilitation medicine center, Fuxing hospital, capital medical university

Locations

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Fuxing hospital, capital medical university

Beijing, , China

Site Status

Countries

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China

Central Contacts

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Lu Song

Role: CONTACT

+86 15010852973

Facility Contacts

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Yong Wang

Role: primary

010-88062907

Other Identifiers

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songlu20210320

Identifier Type: -

Identifier Source: org_study_id