Impact of Patient's Therapeutic Education in APA and Dietetic on Radiotherapy Reproducibility Sessions for Prostate Cancer

NCT ID: NCT04832113

Last Updated: 2023-08-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

216 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-06-21

Study Completion Date

2025-04-30

Brief Summary

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The primary objective of this study is to evaluate the impact of Patient's Therapeutic Education (PTE) in Adapted Physical Activity (APA) ans dietetic on the reduction of interventions number on rectal volume (laxative or probe).

The secondary objectives are to evaluate the contribution of Patient's Therapeutic Education (PTE) between the 2 arms on repositionnind during the radiotherapy session, the gastrointestinal toxicity, the need to use laxative or transit regulating treatment or techniques, the quality of life, the undernutrition and food intake, the evolution in eating/hydratation and physical habits.

For the experimetal arm, the satisfaction and the compliance with PTE program will be evaluated, as well as the need of additionnal use of dietary and APA consultations.

Detailed Description

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Prostate cancer is the 3rd cause of cancer mortality in patient aged over 50 years. Radiotherapy treatment plans require specific conditions:

* Reproductibility of patient's positioning (requiring management of bladder and rectal fillings at each session).
* An image-guided treatment consisting in acquiring an image before each session. This pre-treatment Imaging allows the optimal adjustment of the target volume and organs at risk (bladder and rectum).

To allow reproductibility of target volume positioning at each radiotherapy session, it's recommended to have an empty rectum at the time of the radiotherapy preparation scan, and to check repletion before each session.

It's recommended that the patient has a comfortably full bladder to limit the volume of irradiated bladder mucosa. The radiotherapy teams don't have any recommendations concerning the rectum and manage this problem session by session, according to the repositioning Imaging of the current day.

According to a pilot study carried out in 2017 in the radiotherapy department of the Léon Bérard center, an intervention for a dilated rectum (probe or laxative) was necessary for an average of 25% of session per patient.

These rectal problems can be partly explained by the age (60-80 years) and sedentary lifestyle of patients with prostate cancer. Physical activities, adapted hydratation and changes in eating habits are an integral part of the constipation and flatulence prevention.

Conditions

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Prostate Cancer

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Patient Therapeutics Education (PTE)

Educational diagnosis prior radiotherapy and participation to Patient Therapeutics Education (PTE) in Adapted Physical Activity (APA) and dietetic sessions. In addition to conventional support (dietary and hydration advice).

Group Type EXPERIMENTAL

Adapted Physical Activity and Dietetic

Intervention Type OTHER

session in addtion conventional management dietetic, hydratation and physical activity

Conventional support

Dietary and hydration advices

Group Type OTHER

conventional management

Intervention Type OTHER

Dietary and hydratation advices according to the recommendations

Interventions

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Adapted Physical Activity and Dietetic

session in addtion conventional management dietetic, hydratation and physical activity

Intervention Type OTHER

conventional management

Dietary and hydratation advices according to the recommendations

Intervention Type OTHER

Other Intervention Names

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Follow-up of Adapted Physical Activity and Dietetic Hydratation conventional management dietary and hydratation

Eligibility Criteria

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Inclusion Criteria

I1: Age \>= 18 years old.

I2: Patient with prostatic adenocarcinoma with indication for first-line or post-operative radiotherapy (adjuvant or biologic recurrence).

I3: Patient able to practice a physical activity (certificate of aptitude for adapted physical activity).

I4: Life expectancy greater than 6 months.

I5: Absence of chronic inflammatory intestinal disease or intestinal surgery.

I6: Signed informed consent.

I7: Patient covered by a medical insurance.

I8. At least 20 sessions of radiotherapy planned

Exclusion Criteria

E1: Patient does not understand and cannot read French.

E2: Patient followed for a psychiatric pathology or presenting cognitive disorders.

E3: Inability to comply with study follow-up goegraphical, social or psychological reasons.

E4: Patient requiring tutorship or curatorship or patient deprived of liberty.

E5: Participation to another clinical trial which may interfere with principal Endpoint assessment.
Minimum Eligible Age

18 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Centre Leon Berard

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Pascale Roux

Role: PRINCIPAL_INVESTIGATOR

Centre Leon Berard

Locations

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Chu de saint etienne

Saint-Etienne, Rhône-Alpes Auvergne, France

Site Status NOT_YET_RECRUITING

Groupe Hospitalier Mutualiste de Grenoble Institut Daniel HOLLARD

Grenoble, , France

Site Status RECRUITING

Centre Hospitalier Lyon Sud

Pierre-Bénite, , France

Site Status NOT_YET_RECRUITING

Centre Eugène Marquis

Rennes, , France

Site Status RECRUITING

Institut de Cancérologie de l'Ouest René Gauducheau

Saint-Herblain, , France

Site Status NOT_YET_RECRUITING

Countries

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France

Central Contacts

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Séverine METZGER

Role: CONTACT

+33478782786

Pascale Roux

Role: CONTACT

+33478787200

Facility Contacts

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Thomas REYNAUD, MD

Role: primary

Role: backup

Olivia DIAZ, MD

Role: primary

Samy HORN, MD

Role: primary

Manon BATY, MD

Role: primary

Stéphane SUPIOT, MD

Role: primary

Other Identifiers

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ET20-0284 ETADAPT

Identifier Type: -

Identifier Source: org_study_id

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