BIOTRONIK Dynetic-35 Stent for the Treatment of Peripheral Iliac Lesions

NCT ID: NCT04830228

Last Updated: 2023-12-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

160 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-08-10

Study Completion Date

2028-02-28

Brief Summary

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BIOTRONIK cobalt chromium balloon-expandable Dynetic-35 stent in association with Passeo-35 Xeo peripheral dilation catheter for the treatment of peripheral iliac lesions

Detailed Description

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Prospective, international, multi-center, single-arm study with up to 60 months follow up to evaluate safety and effectiveness of BIOTRONIK's Dynetic-35 stent associated with the use of Passeo-35 Xeo for the treatment of peripheral artery disease (PAD) in subjects with atherosclerotic disease in iliac arteries

Conditions

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Peripheral Artery Disease

Keywords

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Iliac arteries

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Interventions

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Ballon expandable stent and PTA

Endovascular treatment for the peripheral artery disease of the Iliac artery

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. Subject is ≥ 18 years or the minimum age required for legal adult consent in the country of enrolment
2. Subject is capable (no legally authorized representative allowed) to provide written informed consent as approved by the Institutional Review Board (IRB)/Ethics Committee (EC) of the respective clinical site prior to any study related procedure
3. Subject has provided written informed consent before any study specific test or procedure and is willing to comply with all protocol and follow-up requirements
4. De novo, restenotic or occluded lesion(s) representing atherosclerotic lesion(s) in the iliac arteries
5. Reference lumen (vessel) diameter between 5mm and 10mm
6. The target lesion can be successfully crossed with a guide wire
7. The target lesion length is ≤ 100 mm
8. Subjects has more than 70% stenosis in target lesion
9. Subject has an evidence of a patent profunda femoris or superficial femoral artery in the target limb
10. Subject has symptomatic iliac artery occlusive disease defined as Rutherford category 2 or higher eligible for stenting

Exclusion Criteria

1. Subject is pregnant and/or breastfeeding or planning to become pregnant during the course of the study.
2. Subject is with a current medical condition with a life expectancy of less than one year.
3. Pre-existing target iliac artery aneurysm or perforation or dissection
4. Any medical condition that in the opinion of the investigator poses an unacceptable risk for implant of a stent according to the study indications like, sensitivity to metal ions, intolerance to contrast or antiplatelet, anticoagulant or thrombolytic medications required per the protocol
5. Abdominal aortic aneurysm (AAA) contiguous to the iliac artery target lesion requiring treatment
6. The subject is currently participating in an investigational drug, biologic, or another device study and has not reached their primary endpoint yet
7. Refuses blood transfusion
8. Chronic renal insufficiency (Serum creatinine \>2.5 mg/dL within 30 days prior to index procedure)
9. Subject has IFU listed contraindication(s)
10. Subject has in-stent restenosis
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Biotronik AG

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Marianne Brodmann, Prof. Dr.

Role: PRINCIPAL_INVESTIGATOR

Substitute Head of the Clinical Division of Angiology, Department of Internal Medicine

Locations

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LKH Univ.-Klinikum Graz, Ambulanz für Angiologie

Graz, , Austria

Site Status

Zol Genk

Genk, , Belgium

Site Status

UZ Gent

Ghent, , Belgium

Site Status

Regionaal Ziekenhuis Heilig Hart Tienen

Tienen, , Belgium

Site Status

Az Jan Potaels Vilvoorde

Vilvoorde, , Belgium

Site Status

Hôpital Privé du grand Narbonne

Narbonne, , France

Site Status

Hôpital Ambroise Paré

Paris, , France

Site Status

Klinikum Bayreuth

Bayreuth, , Germany

Site Status

Universitätsklinikum Essen

Essen, , Germany

Site Status

Diakonissenkrankenhaus

Flensburg, , Germany

Site Status

Universitätsklinikum Jena

Jena, , Germany

Site Status

St. Franziskushospital Münster

Münster, , Germany

Site Status

Universitätsklinikum Tübingen

Tübingen, , Germany

Site Status

Semmelweis University Hospital

Budapest, , Hungary

Site Status

Pauls Stradins Clinical University Hospital

Riga, , Latvia

Site Status

Countries

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Austria Belgium France Germany Hungary Latvia

Other Identifiers

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C1903

Identifier Type: -

Identifier Source: org_study_id