"Comparison of Two Methods of Securing Endotracheal Tubes in Intensive Care : Elastic Adhesive Strips vs Lace In A Protective Sheath."

NCT ID: NCT04819425

Last Updated: 2023-11-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

768 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-06-28

Study Completion Date

2023-08-10

Brief Summary

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Every year, in France, nearly 100,000 patients hospitalized in intensive care more than 48 hours require invasive respiratory assistance via an endotracheal tube.

Appropriate tube fixation is essential to ensure effective ventilation while minimizing potential complications such as accidental extubations. However, the fixation system chosen may lead to peribuccal lesions such as bedsores, shearing or cutaneous-mucous tear. These lesions are painful for patients and often unsightly as scar may remain.

There are no formal recommendations for the use of any type of fixing system. Thus, systems used to secure the endotracheal tube vary from one ICU to another.

The objective of this study is to demonstrate that the fixing strategy by elastic adhesive tape reduces the risk of developing a peribuccal lesion during the time of the endotracheal tube's maintenance.

Detailed Description

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Conditions

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Intubation Complication

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Cluster and Crossover
Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Elastic Adhesive Strips

Endotracheal tube fixed by elastic adhesive tape (Tensoplast type adhesive tape):

The adhesive tape will be attached to the patient's face (opposite side to the endotracheal tube) and then two turns around the endotracheal tube will be made. The rest of the adhesive tape will be attached to the other side of the face (side of the endotracheal tube).

The laminated tape will be kept on the adhesive tape until it passes over the neck in order to avoid adhering to the hair.

Finally, the end of the adhesive tape will be replaced on the part already attached to the patient.

It will be changed daily and after stain or examinations if necessary.

Group Type EXPERIMENTAL

Elastic Adhesive Strips

Intervention Type DEVICE

Securement of Endotracheal tube with Elastic Adhesive Strips

Lace in A Protective Sheath

A loop is made with the lace then the endotracheal tube is passed through the loop. The loop is tightened by pulling each side on the remaining cords and a knot is made on one side of the fastener.

It will be changed daily and after stain or examinations if necessary.

Group Type ACTIVE_COMPARATOR

Lace in A Protective Sheath

Intervention Type DEVICE

Securement of Endotracheal tube with Lace in A Protective Sheath

Interventions

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Elastic Adhesive Strips

Securement of Endotracheal tube with Elastic Adhesive Strips

Intervention Type DEVICE

Lace in A Protective Sheath

Securement of Endotracheal tube with Lace in A Protective Sheath

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Patient hospitalized in Intensive Care Unit
* Age over 18
* Intubation for estimated duration \> 48h
* Patient treated with vasopressors
* Patient or relative who received the information and are not opposed to study participation or patient included under the emergency procedure in the absence of contactable family members.

Exclusion Criteria

* Pre-existing face lesions at ICU admission along the path of the endotracheal tube fixing.
* Admitted patient already intubated upon transfer from another ICU
* Nasotracheal intubation
* Patient in isolation for suspected COVID or clinically proven COVID
* Admitted tracheotomized patient
* Pregnant, nursing, parturient woman
* Lack of social security affiliation
* Moribund
* Incapable major (under guardianship, curatorship)
* Patient deprived of liberty by court order
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Departemental Vendee

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Vanessa ZINZONI

Role: PRINCIPAL_INVESTIGATOR

CHD Vendée

Locations

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Centre Hospitalier d'Angoulême

Angoulême, , France

Site Status

CH Victor Dupouy

Argenteuil, , France

Site Status

Centre Hopitalier La Rochelle

La Rochelle, , France

Site Status

Centre Hospitalier Le Mans

Le Mans, , France

Site Status

Groupe Hospitalier Bretagne Sud

Lorient, , France

Site Status

CHU Nantes Hôtel Dieu

Nantes, , France

Site Status

Centre Hospitalier Régional d'Orléans

Orléans, , France

Site Status

CHI Poissy - Saint-Germain-en-Laye

Poissy, , France

Site Status

CHU de Poitiers

Poitiers, , France

Site Status

Hôpital Nord Laennec

Saint-Herblain, , France

Site Status

CH Saint-Nazaire

Saint-Nazaire, , France

Site Status

CHU La Réunion GHSR

Saint-Pierre, , France

Site Status

CHU de Tours

Tours, , France

Site Status

Countries

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France

References

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Zinzoni V, Planche L, Le Potier S, Robin L, Le Parco C, Terrat P, Leroyer MH, Atger R, Dauvergne JE, Muller L, Fontaine L, Morand C, Dennemont P, Paillard O, Vastral S, Dardaine B, Le Guillou S, Maquigneau N, Martin S, Lacherade JC. Impact of two endotracheal tube fixation on the incidence of peri-oral lesions: Elastic adhesive strips versus cord in a protective sheath. Study protocol for a cluster cross-over randomized trial. PLoS One. 2024 Feb 8;19(2):e0297349. doi: 10.1371/journal.pone.0297349. eCollection 2024.

Reference Type DERIVED
PMID: 38330026 (View on PubMed)

Other Identifiers

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CHD032-20

Identifier Type: -

Identifier Source: org_study_id