Clinical Features of COVID-19 Patients

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-03-13

Study Completion Date

2023-11-13

Brief Summary

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The data were retrospectively collected during the first and the second wave of epidemic in COVID-19 patients with Severe Acute Respiratory Syndrome Coronavirus 2, at the moment of intensive care unit admission and during the in intensive care unit staying.

Detailed Description

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At the moment of intensive care unit admission and during the in intensive care unit staying, the following data were collected: peripheral lymphocyte subsets were measured by multiple-color flow cytometry, chest computed tomography and ultrasonography scans, arterial blood gas parameters (pH, partial pressure of carbon dioxide, partial pressure of oxygen, concentration of hydrogen carbonate, base excess, and arterial oxygen saturation), and pain assessed by using numeric rating scale.

Conditions

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Covid19 Acute Respiratory Distress Syndrome Ventilatory Failure

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Interventions

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peripheral lymphocytes subsets

The data were collected during the first and the second wave of epidemic in COVID-19 patients with acute respiratory distress syndrome. At the moment of hospitalization, at the moment of intensive care unit admission and during the in intensive care unit staying, the following data were collected: peripheral lymphocyte subsets were measured by multiple-color flow cytometry, chest computed tomography and ultrasonography scans (lung ultrasound score, diaphragmatic thickness and motion), arterial blood gas analysis parameters (pH, partial pressure of carbon dioxide, partial pressure of oxygen, concentration of hydrogen carbonate, base excess, and arterial oxygen saturation ), and pain assessed by using numeric rating scale. Macroscopic and microscopic hypopharynx and larynx damages were also evaluated by video-laryngoscopy and light miscoscopy.

Intervention Type DIAGNOSTIC_TEST

Other Intervention Names

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Chest computed tomography Chest ultrasonography scan arterial blood gas analysis pain

Eligibility Criteria

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Inclusion Criteria

* COVID-19 patients
* Acute respiratory distress syndrome
* needing of ventilatory support

Exclusion Criteria

* asymptomatic COVID-19 patients
* few symptoms
* mild symptoms
* without needing of ventilatory support

Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Emiliano Petrucci

Medical Doctor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Franco Marinangeli, MD

Role: STUDY_CHAIR

ASL 1 Avezzano Sulmona L'Aquila

Locations

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San Salvatore Academic Hospital

L’Aquila, , Italy

Site Status

Countries

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Italy

Other Identifiers

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26100/21

Identifier Type: -

Identifier Source: org_study_id