Lung Cancer Patients' Attitudes to a Second Course of Radiotherapy
NCT ID: NCT04813068
Last Updated: 2021-05-28
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
30 participants
OBSERVATIONAL
2021-04-16
2022-06-30
Brief Summary
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One possible treatment is a second course of radiotherapy (re-irradiation). Early studies show that a re-irradiation may cause significant side effects like breathlessness or problems swallowing, but may control the cancer for a long period of time. We want to do a clinical trial to investigate if re-irradiation improves cancer control compared to other treatments to help guide treatment for patients with recurrent disease.
Before we can go ahead with the trial, we would like to talk to patients who are have completed radiotherapy to find out what are their feelings about having a second course of radiotherapy if needed, and how the side effects from the initial course of radiotherapy or the projected side-effects from the second course would affect that decision.
This information is vitally important to help develop a trial about re-irradiation in lung cancer as it will demonstrate if patients would accept a second course of radiotherapy, and, by accounting for patient concerns in the trial design, will make it more likely to recruit well.
This study will perform telephone interviews with patients five weeks after completing a course of radical radiotherapy for lung cancer at the Beatson Cancer Centre. We expect to interview 16-30 patients. This study will run over the course of 1 year. This research is funded by the Beatson Cancer Charity and The University of Glasgow.
Detailed Description
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Conditions
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Study Design
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COHORT
RETROSPECTIVE
Study Groups
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Interview arm
Group of patients who have agreed to have a qualitative interview on the topic of recurrence of lung cancer
Semi-structured interview
Semi-structured interview to identify attitudes to re-irradiation in lung cancer
Interventions
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Semi-structured interview
Semi-structured interview to identify attitudes to re-irradiation in lung cancer
Eligibility Criteria
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Inclusion Criteria
* Pathological or radiological diagnosis of non-small cell lung cancer
* Undergoing radical radiotherapy to the thorax using the following fractionations (55 Gray in 20 fractions, 54 Gray in 36 fractions or any Stereotactic Ablative Body Radiotherapy (SABR) fractionation that delivers a biological effective dose of greater than 100Gy10) as part of their primary lung cancer treatment at time of study enrolment
* Patients receiving concurrent and/or adjuvant systemic therapies are permitted
* Radiotherapy is delivered in the Beatson West of Scotland Cancer Centre
* Signed, written informed consent
* Willing and able to complete study processes
Exclusion Criteria
18 Years
ALL
No
Sponsors
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University of Glasgow
OTHER
The Beatson Cancer Charity
UNKNOWN
NHS Greater Glasgow and Clyde
OTHER
Responsible Party
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Principal Investigators
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Stephen Harrow, PhD
Role: PRINCIPAL_INVESTIGATOR
NHS Greater Glasgow and Clyde
Locations
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The Beatson West of Scotland Cancer Centre
Glasgow, , United Kingdom
Countries
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Central Contacts
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Facility Contacts
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Robert J Rulach, MBChB
Role: primary
Provided Documents
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Document Type: Study Protocol
Other Identifiers
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GN20ON632
Identifier Type: -
Identifier Source: org_study_id