Effectiveness of Pharmaceutical Interventions in Hospitalized Patients

NCT ID: NCT04800900

Last Updated: 2022-04-12

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 332 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2021-02-04
• Study Completion Date: 2022-01-30

Brief Summary

The presence of multimorbidities is very common among the elderly, which become major consumers of medicines. The process of prescribing medicines for the elderly should be done with caution, as the use of some medications may present more risks than benefits in this range age. Potentially inappropriate prescribing for the elderly has become a global concern for the promotion of an adequate pharmacotherapy, it becomes essential to be aware of the effectiveness and safety of medicines and the knowledge of which drugs whose risks of serious adverse reactions outweigh the benefit of your referral. In this sense, the present study has aim to evaluate the effectiveness of pharmaceutical interventions in frequency of omission of drugs with proven efficacy for cardiovascular diseases and promotion of treatment prescription inappropriate and polypharmacy. A prospective quasi experimental before and after study will be carried out in elderly patients diagnosed with cardiovascular disease admitted to the Ana Nery hospital, Salvador, Bahia, Brazil. A convenience sample will be collected, the data will be released and revised in a database built in the SPSS software and analyzed in the program statistic R and SPSS. At the end of the study, it is expected a decrease in the frequency of omission of medications and promotion of prescription drugs inappropriate.

Conditions

Safety Issues

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: OTHER
• Blinding Strategy: NONE

Study Groups

Pharmaceutical intervention

A pharmacist will analyse patient's prescription, identify if there is prescribing omission and inappropriated drug prescribed and when necessary will require to doctors

Group Type: EXPERIMENTAL

Pharmaceutical intervention

Intervention Type: OTHER

A pharmacist will analyse patient's prescription, identify if there is prescribing omission and inappropriated drug prescribed and when necessary will require to doctors deprescribe or introduce or remove prescribed drugs

Interventions

Pharmaceutical intervention

A pharmacist will analyse patient's prescription, identify if there is prescribing omission and inappropriated drug prescribed and when necessary will require to doctors deprescribe or introduce or remove prescribed drugs

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Clinical diagnosis of cardiovascular disease
• Discharge after 24 hours

Exclusion Criteria

• Death

• Minimum Eligible Age: 60 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Federal University of Bahia

OTHER

Sponsor Role: lead

Responsible Party

Márcio Galvão Guimarães de Oliveira

Clinical Professor of Pharmacy and Evidence-based Health Care

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Hospital Ana Nery

Salvador, Estado de Bahia, Brazil

Countries

Brazil

References

Gama RS, Passos LC, Amorim WW, Souza RM, Oliveira MG. Effectiveness of Pharmacist Interventions in Improving Medication Use in Hospitalised Older Patients Diagnosed With Cardiovascular Diseases: INFAR Before-and-After Study. J Eval Clin Pract. 2025 Jun;31(4):e70190. doi: 10.1111/jep.70190.

Reference Type: DERIVED

PMID: 40581959 (View on PubMed)

Other Identifiers

41325820

Identifier Type: -

Identifier Source: org_study_id