Alpha-1-Antitrypsin-Deficiency in COVID-19

NCT ID: NCT04799873

Last Updated: 2025-05-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

10 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-04-08

Study Completion Date

2020-12-01

Brief Summary

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The blood concentrations of alpha-1-antitrypsin are monitored during COVID-19. The clinical course of patients that received AAT infusion for clinical indication is monitored.

Detailed Description

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The blood concentrations of alpha-1-antitrypsin are monitored during COVID-19. The clinical course of patients that received AAT infusion for clinical indication is monitored. Clinical outcomes, blood inflammatory markers, and virus load are monitored.

Conditions

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Covid19

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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AAT( Alpha 1 Antitrypsin)

AAT administration based on clinical indication

Intervention Type DRUG

Other Intervention Names

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AAT administration based on clinical indication

Eligibility Criteria

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Inclusion Criteria

* Infection with SARS-COV2
* Age over 18 years

Exclusion Criteria

* Unability to consent
* Invasive ventilation
Minimum Eligible Age

18 Years

Maximum Eligible Age

110 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Universität des Saarlandes

OTHER

Sponsor Role lead

Responsible Party

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Robert Bals

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Robert Bals

Role: PRINCIPAL_INVESTIGATOR

UDS

Locations

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Saarland University

Homburg, Saarland, Germany

Site Status

Countries

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Germany

Other Identifiers

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CORSAAR-AAT-001

Identifier Type: -

Identifier Source: org_study_id

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