Malt-derived Ingredients and Their Prolactinotrophic Effects

NCT ID: NCT04796259

Last Updated: 2022-02-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

12 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-02-05

Study Completion Date

2021-05-07

Brief Summary

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This proof-of-concept study aims to investigate whether malt-derived ingredients have acute prolactinotrophic effects in healthy women of child-bearing age.

Detailed Description

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Conditions

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Acute Response to Food Ingredient Consumption

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Negative control

Water

Group Type NO_INTERVENTION

No interventions assigned to this group

Positive control

Non-alcoholic beer solids

Group Type ACTIVE_COMPARATOR

Non-alcoholic beer solids

Intervention Type DIETARY_SUPPLEMENT

Solution with non-alcoholic beer solids

Intervention 1

Malt ingredient I

Group Type EXPERIMENTAL

Malt ingredient

Intervention Type DIETARY_SUPPLEMENT

Solution with malt-derived ingredient

Intervention 2

Malt ingredient II

Group Type EXPERIMENTAL

Malt ingredient

Intervention Type DIETARY_SUPPLEMENT

Solution with malt-derived ingredient

Interventions

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Malt ingredient

Solution with malt-derived ingredient

Intervention Type DIETARY_SUPPLEMENT

Non-alcoholic beer solids

Solution with non-alcoholic beer solids

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Subjects who have/are

1. Willing and able to provide written informed consent
2. Healthy women aged 18 to 40.
3. BMI in the range of 18 to 30.
4. Willing to undergo an experiment in the follicular phase of the menstrual cycle i.e. day 0 to 14 of the menstrual cycle starting from the first day of the period.

Exclusion Criteria

* Subjects who have/are
* Allergic to tested products
* Under regular medication including oral contraceptive pills or other form of hormonal replacement therapy.
* Under medications which affects prolactin levels.
* Pregnant or lactating or planning to conceive during the study period.
* Smokers, or excessive alcohol consumption (alcohol intake higher than 2 servings per day. A serving is 0.4 dl of strong alcohols, 1 dl of red or white wine, or 3 dl of beer) or other substance abuse.
* Not willing and/or not able to comply with the study procedures and requirements.
* Suffering from pre-existing medical conditions and chronic illnesses that in the opinion of the investigator may interfere with the study.
* Family or hierarchical relationships with research team members
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Société des Produits Nestlé (SPN)

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jose M. Ramos Nieves, M.Sc.; Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Société des Produits Nestlé S.A./NIHS

Pamela Sun

Role: STUDY_DIRECTOR

Société des Produits Nestlé S.A./CIL

Locations

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Société des produits Nestlé/Metabolic Unit

Lausanne, , Switzerland

Site Status

Countries

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Switzerland

Other Identifiers

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20.21.NRC

Identifier Type: -

Identifier Source: org_study_id

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