Trial Outcomes & Findings for A Study of Treprostinil Palmitil Inhalation Powder (TPIP) In Pulmonary Arterial Hypertension (PAH) (NCT NCT04791514)

NCT ID: NCT04791514

Last Updated: 2023-09-22

Results Overview

Recruitment status

TERMINATED

Study phase

PHASE2

Target enrollment

1 participants

Primary outcome timeframe

Up to 150 days

Results posted on

2023-09-22

Participant Flow

The study was terminated by the Sponsor due to low enrolment. As only 1 participant was enrolled in this study, no data is reported here, in order to protect and maintain participant privacy/confidentiality.

Participant milestones

Participant milestones
Measure
Treprostinil Palmitil Inhalation Powder (TPIP)
Participant received a single dose of TPIP 112.5 micrograms (μg) via oral inhalation on Day 1. The participant then entered into a 16-week Extended Use Treatment (EUT) Period during which TPIP, administered via oral inhalation, was titrated up to a mean daily dose of 320 μg.
Overall Study
STARTED
0
Overall Study
COMPLETED
0
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

A Study of Treprostinil Palmitil Inhalation Powder (TPIP) In Pulmonary Arterial Hypertension (PAH)

Baseline characteristics by cohort

Baseline data not reported

PRIMARY outcome

Timeframe: Up to 150 days

Population: The study was terminated by the Sponsor due to low enrolment. As only 1 participant was enrolled in this study, no data is reported here, in order to protect and maintain participant privacy/confidentiality.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Day 1: Pre-treatment (Baseline), 8 and 24 hours post-treatment

Population: The study was terminated by the Sponsor due to low enrolment. As only 1 participant was enrolled in this study, no data is reported here, in order to protect and maintain participant privacy/confidentiality.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Pre-dose and multiple timepoints post-dose up to Day 2

Population: The study was terminated by the Sponsor due to low enrolment. As only 1 participant was enrolled in this study, no data is reported here, in order to protect and maintain participant privacy/confidentiality.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Pre-dose and multiple timepoints post-dose up to Day 2

Population: The study was terminated by the Sponsor due to low enrolment. As only 1 participant was enrolled in this study, no data is reported here, in order to protect and maintain participant privacy/confidentiality.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Pre-dose and multiple timepoints post-dose up to Day 2

Population: The study was terminated by the Sponsor due to low enrolment. As only 1 participant was enrolled in this study, no data is reported here, in order to protect and maintain participant privacy/confidentiality.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Pre-dose and multiple timepoints post-dose up to Day 2

Population: The study was terminated by the Sponsor due to low enrolment. As only 1 participant was enrolled in this study, no data is reported here, in order to protect and maintain participant privacy/confidentiality.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Pre-dose and multiple timepoints post-dose up to Day 2

Population: The study was terminated by the Sponsor due to low enrolment. As only 1 participant was enrolled in this study, no data is reported here, in order to protect and maintain participant privacy/confidentiality.

Outcome measures

Outcome data not reported

Adverse Events

Treprostinil Palmitil Inhalation Powder (TPIP)

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Insmed Medical Information

Insmed Incorporated

Phone: 1-844-446-7633

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place

Restriction type: LTE60