Prolactin Hormone in Oral Lichen Planus

NCT ID: NCT04785703

Last Updated: 2021-03-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-06-19

Study Completion Date

2020-12-10

Brief Summary

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Oral lichen planus (OLP) is one of the most common mucosal diseases with autoimmune etio-pathogenesis with involvement of various cytokines similar to psoriasis.It generally occurs more commonly in females, in a ratio of 3:2. prolactin (PRL),It is a peptide hormone that has a role in autoimmune related diseases like systemic lupus erythematosus and , rheumatoid Artheritis. The role of PrL in OLP pathogenesis was never investigated.the aim of this study is to investigate the expression of PRL receptors in tissue biopsies of OLP patients.

Detailed Description

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Conditions

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Oral Lichen Planus

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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oral lichen planus group

patients with chronic bollus erosive lichen planus

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* patients with oral lichen planus
* systemically healthy

Exclusion Criteria

* oral lichenoid lesions
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Al-Azhar University

OTHER

Sponsor Role collaborator

October University for Modern Sciences and Arts

OTHER

Sponsor Role lead

Responsible Party

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Naglaa Elwakeel

professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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October University for modern sciences and arts

Giza, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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REC18-048

Identifier Type: -

Identifier Source: org_study_id

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