Intraoperative Berger Space Imaging (IBSI)

NCT ID: NCT04775849

Last Updated: 2021-03-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-05-20

Study Completion Date

2022-11-30

Brief Summary

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The investigational device is an approved femtosecond laser (FSL) device with an integrated imaging system to perform certain steps of the cataract procedure. The FSL will perform anterior capsulotomy and lens fragmentation in individuals suffering from age-related cataract with need of cataract surgery.

The laser will be reduced to image the Berger space. If not visible, the space will be enhanced with BSS and Volon A to visualize the BS.

Cataract surgery will be performed in subjects who have signed an informed consent form. Macula thickness will be measured with Spectralis OCT on screening date.

Postoperative examinations will be implemented in accordance with the approved investigational plan on subjects and includes: visual acuity, slitlamp examination and retinal oct imaging.

Detailed Description

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Conditions

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Cataract Macula Edema

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Cataract surgery will be performed in individuals with age-related cataract.
Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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Intraoperative Berger Space Imaging

Intraoperative OCT imaging of the space between the posterior capsule and the anterior hyaloid

Group Type EXPERIMENTAL

Femtosecond Laser

Intervention Type DEVICE

Femtosecond Laser assisted Cataract Surgery will be performed uni- or bilateral

Interventions

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Femtosecond Laser

Femtosecond Laser assisted Cataract Surgery will be performed uni- or bilateral

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Bilateral age-related cataract necessitating phacoemulsification extraction and posterior IOL implantation
* Age: 40 to 90 (females of childbearing age will be interviewed if pregnancy is possible)
* Preoperative pupil size in mydriasis ≥ 6.0 mm

Exclusion Criteria

* Preceding ocular surgery or trauma
* Pseudoexfoliation
* Recurrent intraocular inflammation of unknown etiology
* Uncontrolled glaucoma
* Uncontrolled systemic or ocular disease
* Blind fellow eye
* Microphthalmus
* Corneal abnormality
* History of uveitis/iritis
* Iris neovascularization
* Proliferative diabetic retinopathy
* Macular degeneration or any other relevant macular diseases
* Pregnancy
Minimum Eligible Age

40 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medical University of Vienna

OTHER

Sponsor Role lead

Responsible Party

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Rupert Menapace

Clinical Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Rupert Menapace, MD

Role: PRINCIPAL_INVESTIGATOR

Medical Universitiy of Vienna

Locations

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Medical University of Vienna

Vienna, , Austria

Site Status RECRUITING

Countries

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Austria

Central Contacts

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Veronika Röggla, MD

Role: CONTACT

0140400 ext. 79450

Christina Leydolt, MD

Role: CONTACT

0140400 ext. 79480

Facility Contacts

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Rupert Menapace, MD

Role: primary

0140400 ext. 66300

Christina Leydolt, MD

Role: backup

0140400 ext. 79480

Other Identifiers

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IBSI - 2258/2018

Identifier Type: -

Identifier Source: org_study_id

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