Spanish Study to Analyze the Histopathological, Ultrastructural and Microbiological Findings Obtained in Autopsies of Patients Who Died Due to COVID-19
NCT ID: NCT04772833
Last Updated: 2021-02-26
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
50 participants
OBSERVATIONAL
2020-06-05
2021-12-31
Brief Summary
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Detailed Description
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The performance of systematic and regulated autopsies can help to manage it. However, despite the need to generate this knowledge and the strong impact on mortality caused by the COVID-19 pandemic, the evidence from post-mortem studies is very limited.
Conditions
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Keywords
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Autopsy group
Patients with COVID-19 infection confirmed by PCR, whose death is related to active COVID-19 infection or its complications.
Autopsy
The subjects deceased will undergo an autopsy to analyze the histopathological, ultrastructural and microbiological findings, related to the COVID-19 disease.
Interventions
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Autopsy
The subjects deceased will undergo an autopsy to analyze the histopathological, ultrastructural and microbiological findings, related to the COVID-19 disease.
Eligibility Criteria
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Inclusion Criteria
* Death related to active infection by COVID-19 or its complications.
* Informed consent given by the subject's relatives to perform an autopsy according to the autonomous community requirements.
* Informed consent given by the subject's relatives for the inclusion of samples in the Biobank.
Exclusion Criteria
* Advanced or terminal chronic disease.
* Inadequate security level of the autopsy room.
ALL
No
Sponsors
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Spanish Society of Infectious Diseases and Clinical Microbiology
UNKNOWN
Spanish Society of Pathological Anatomy
UNKNOWN
Maimónides Biomedical Research Institute of Córdoba
OTHER
Responsible Party
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Principal Investigators
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Antonio Rivero Román, MD
Role: PRINCIPAL_INVESTIGATOR
Spanish Society of Infectious Diseases and Clinical Microbiology. Reina Sofía University Hospital.
Teresa Hermida Romero, MD
Role: STUDY_CHAIR
Spanish Society of Pathological Anatomy. A Coruña University Hospital
Xavier Matias--Guiu Guia, MD
Role: STUDY_CHAIR
Spanish Society of Pathological Anatomy. Bellvitge University Hospital
Jordi Vila Estapé, MD
Role: STUDY_CHAIR
Spanish Society of Infectious Diseases and Clinical Microbiology. Barcelona Clinic University Hospital.
Locations
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Marqués de Valdecilla University Hospital
Santander, Cantabria, Spain
Puerta de Hierro University Hospital
Majadahonda, Madrid, Spain
Navarra University Hospital
Pamplona, Navarre, Spain
Barcelona Clinic University Hospital
Barcelona, , Spain
Reina Sofía University Hospital
Córdoba, , Spain
Ramón y Cajal University Hospital
Madrid, , Spain
Fundación Jiménez Díaz University Hospital
Madrid, , Spain
12 de Octubre University Hospital
Madrid, , Spain
Virgen del Rocío University Hospital
Seville, , Spain
Araba University Hospital
Vitoria-Gasteiz, Álava, Spain
Countries
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Central Contacts
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Facility Contacts
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Javier Gómez Román, MD
Role: primary
Clara Salas Antón, MD
Role: primary
Antonio Ramos, MD
Role: backup
Alicia Córdoba Iturriagagoitia, MD
Role: primary
Carlos Ibero Esparza, MD
Role: backup
Jordi Vila Estapé, MD
Role: primary
Antonio Rivero Román, MD
Role: primary
Rosa Ortega Salas, MD
Role: backup
José Palacios Calvo, MD
Role: primary
Santiago Moreno, MD
Role: backup
Federico Rojo, MD
Role: primary
Laura Prieto, MD
Role: backup
José L Rodríguez Peralto, MD
Role: primary
Rafael Rubio, MD
Role: backup
Enrique De Álava, MD
Role: primary
José M Cisneros, MD
Role: backup
Isabel Guerra Merino, MD
Role: primary
Joseba Portu, MD
Role: backup
Other Identifiers
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NECROVID
Identifier Type: -
Identifier Source: org_study_id