Log2Lose: Incenting Weight Loss and Dietary Self-monitoring in Real-time to Improve Weight Management Among Adults With Obesity

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

706 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-05-13

Study Completion Date

2025-04-10

Brief Summary

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This study involves an evaluation of whether providing small incentives weekly for dietary self-monitoring and/or weight loss improves short- and long-term weight loss. Participants can expect to be on study for 18 months.

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Detailed Description

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In this two-site, randomized, single-masked, longitudinal 2x2 factorial study, called Log2Lose, adults with obesity from Madison, WI and Durham, NC will be offered a 78 week, evidence-based behavioral weight management program comprising an incentivized weight loss intervention for 26 weeks (Phase I), an incentivized weight loss maintenance intervention for 26 weeks (Phase II), and a non-incentivized weight maintenance intervention for 26 weeks (Phase III). Participants will be randomized in a 2x2 design to receive adjunctive incentives for either weekly weight loss or dietary self-monitoring, both, or neither. The investigators will assess the proportion of participants achieving clinically significant weight loss of greater than or equal to 5 percent at the end of each phase.

All participants will participate in an 18-month weight management program delivered via videoconference.

Conditions

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Obesity

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

FACTORIAL

2 (incentives for dietary self-monitoring: yes vs. no) x 2 (incentives for weight loss: yes vs. no)

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Combined

Weekly incentives for dietary self-monitoring and weight loss

Group Type EXPERIMENTAL

Incentives for dietary self-monitoring and weight loss

Intervention Type BEHAVIORAL

Participants can earn up to $300 during the trial for achieving adequate dietary self-monitoring and weight loss

Dietary self-monitoring

Weekly incentives for dietary self-monitoring

Group Type EXPERIMENTAL

Incentives for dietary self-monitoring

Intervention Type BEHAVIORAL

Participants can earn up to $300 during the trial for achieving adequate dietary self-monitoring

Weight loss

Weekly incentives for weight loss

Group Type EXPERIMENTAL

Incentives for weight loss

Intervention Type BEHAVIORAL

Participants can earn up to $300 during the trial for achieving weight loss

Control

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Incentives for dietary self-monitoring and weight loss

Participants can earn up to $300 during the trial for achieving adequate dietary self-monitoring and weight loss

Intervention Type BEHAVIORAL

Incentives for dietary self-monitoring

Participants can earn up to $300 during the trial for achieving adequate dietary self-monitoring

Intervention Type BEHAVIORAL

Incentives for weight loss

Participants can earn up to $300 during the trial for achieving weight loss

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* BMI ≥30 kg/m2
* Desire to lose weight
* Agrees to attend outcome visits per protocol
* Available for class times
* Transportation and ability to attend in-person study visits at baseline (screening), 26, 52, and 78 weeks
* Able to stand for weight measurements without assistance
* Able to speak and read English
* Able to download and use the MyFitnessPal and Fitbit apps daily
* Possess smart phone with data and texting plan
* Have or willing to create a Gmail address
* Able to connect to a video conference call using a smartphone, tablet or computer with a webcam and microphone
* Score of at least 4 out of 6 on a validated cognitive screener

Exclusion Criteria

* Weight \>380 lb
* Weight loss of at least 10 lbs in the month prior to screening
* Currently enrolled or enrolled in previous month in a clinical, research, or community program focusing on lifestyle change that could affect weight
* Current use of weight loss medication
* History of bariatric surgery or planning to have bariatric surgery in the study timeframe
* Residing in a nursing home or receiving home health care
* Impaired hearing
* Significant dementia, drug or alcohol misuse, or unstable psychiatric illness (e.g., schizophrenia, psychosis)
* Current treatment for cancer or being treated for cancer (besides basal cell carcinoma or squamous cell) in the last 6 months
* Use of insulin, sulfonylureas, or meglitinides due to increased risk for hypoglycemia
* Pregnant, breastfeeding, or planning to become pregnant within the study timeframe
* Diuretic medication doses higher than hydrochlorothiazide 25 mg daily, furosemide 40 mg daily, torsemide 20 mg daily, bumetanide 1 mg daily, or any use of metolazone; use of potassium-sparing diuretics is acceptable
* Chronic kidney disease at stage 4 or 5
* Unstable heart disease in the 6 months prior to screening
* Exertional chest pain
* History of ascites requiring paracentesis
* Pain, fainting or other conditions that prohibit mild/moderate exercise

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes