Antifungal Potential of Moringa Olifera Against Otomycosis

NCT ID: NCT04768829

Last Updated: 2022-03-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

EARLY_PHASE1

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-02-18

Study Completion Date

2021-12-01

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

patients with Otomycosis were recognized by an ENT specialist. 20 patients were distributed randomly into two groups. The first group will be treated with Nystatin ear drops twice daily. The second group will be treated with Moringa ear drops. patients will be examined endoscopically by the ENT specialist. patient's swabs will be isolated and analyzed by ELISA.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Inclusion criteria:

(1) Otomycosis .

Exclusion criteria:

1. tympanic membrane perforation;
2. concurrent immune suppression,
3. and concurrent bacterial infection.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Otomycosis

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

moringa extract ear drops
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Placebo group

Nystatin ear drops formulations prepared as intervention except for the addition of Moringa prepared using biodegradable polymers in aseptic condition and tested for sensitivity

Group Type ACTIVE_COMPARATOR

Ear Drop

Intervention Type DRUG

plain ear drop formulation without moringa

Moringa group

Moringa ear drops prepared using biodegradable polymers in aseptic condition and tested for sensitivity

Group Type EXPERIMENTAL

Moringa oleifera leaf 10mg/100ml

Intervention Type DRUG

ear drops

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Moringa oleifera leaf 10mg/100ml

ear drops

Intervention Type DRUG

Ear Drop

plain ear drop formulation without moringa

Intervention Type DRUG

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

ear drops

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

1. Otomycosis
2. ear inflammation

Exclusion Criteria

1. tympanic membrane perforation
2. concurrent immune suppression,
3. concurrent bacterial infection.
Minimum Eligible Age

20 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Minia University

OTHER

Sponsor Role collaborator

Deraya University

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Soad Ali

principle investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Soad A Mohamad

Role: PRINCIPAL_INVESTIGATOR

Deraya University

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Soad A. Mohamad

Minya, Minya Governorate, Egypt

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Egypt

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

S85Motic

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Fungal Resistance in Dermatophyte Infection
NCT06729216 NOT_YET_RECRUITING