Trial Outcomes & Findings for To Assess the Utility of the Point Digit in a Clinical Take-home Study (NCT NCT04755790)

NCT ID: NCT04755790

Last Updated: 2024-01-24

Results Overview

Capacity Assessment of Prosthetic Performance for the Upper Limb (CAPPFUL) provides a comprehensive, performance based measure for upper limb prosthetic use with any upper-limb functional prosthesis at any amputation level through assessment of commonplace activities that take place in various planes of movement. Scale Title: Overall Performance. Scale Minimum: 0. Scale Maximum: 100. Higher score indicates better outcome.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

13 participants

Primary outcome timeframe

Day 0: no prosthesis (pre-fitting)

Results posted on

2024-01-24

Participant Flow

Participant milestones

Participant milestones
Measure
No Prosthesis, Then Prosthesis
Baseline outcome measurements will be performed without a prosthesis Outcome measurements will be performed after the subject has been fit with a prosthesis at 3 different points in time: immediately post-fitting, \~30 days post-fitting, and \~60 days post-fitting Point Digit: Patient is fit with Point Digit partial hand prosthetic system
No Prosthesis (Day 0)
STARTED
13
No Prosthesis (Day 0)
COMPLETED
13
No Prosthesis (Day 0)
NOT COMPLETED
0
Prosthesis (Day 0)
STARTED
13
Prosthesis (Day 0)
COMPLETED
13
Prosthesis (Day 0)
NOT COMPLETED
0
Prosthesis (Day 30)
STARTED
13
Prosthesis (Day 30)
COMPLETED
11
Prosthesis (Day 30)
NOT COMPLETED
2
Prosthesis (Day 60)
STARTED
11
Prosthesis (Day 60)
COMPLETED
11
Prosthesis (Day 60)
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

To Assess the Utility of the Point Digit in a Clinical Take-home Study

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
All Participants
n=13 Participants
Baseline outcome measurements will be performed without a prosthesis Outcome measurements will be performed after the subject has been fit with a prosthesis at 3 different points in time: immediately post-fitting, \~30 days post-fitting, and \~60 days post-fitting Point Digit: Patient is fit with Point Digit partial hand prosthetic system
Age, Categorical
<=18 years
0 Participants
n=5 Participants
Age, Categorical
Between 18 and 65 years
13 Participants
n=5 Participants
Age, Categorical
>=65 years
0 Participants
n=5 Participants
Sex: Female, Male
Female
3 Participants
n=5 Participants
Sex: Female, Male
Male
10 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
3 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
9 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
1 Participants
n=5 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=5 Participants
Race (NIH/OMB)
Asian
1 Participants
n=5 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=5 Participants
Race (NIH/OMB)
Black or African American
0 Participants
n=5 Participants
Race (NIH/OMB)
White
8 Participants
n=5 Participants
Race (NIH/OMB)
More than one race
1 Participants
n=5 Participants
Race (NIH/OMB)
Unknown or Not Reported
3 Participants
n=5 Participants

PRIMARY outcome

Timeframe: Day 0: no prosthesis (pre-fitting)

Capacity Assessment of Prosthetic Performance for the Upper Limb (CAPPFUL) provides a comprehensive, performance based measure for upper limb prosthetic use with any upper-limb functional prosthesis at any amputation level through assessment of commonplace activities that take place in various planes of movement. Scale Title: Overall Performance. Scale Minimum: 0. Scale Maximum: 100. Higher score indicates better outcome.

Outcome measures

Outcome measures
Measure
No Prosthesis, Then Prosthesis
n=11 Participants
Baseline outcome measurements will be performed without a prosthesis Outcome measurements will be performed after the subject has been fit with a prosthesis at 3 different points in time: immediately post-fitting, \~30 days post-fitting, and \~60 days post-fitting Point Digit: Patient is fit with Point Digit partial hand prosthetic system
Capacity Assessment of Prosthetic Performance for the Upper Limb (CAPPFUL)
74.6 scores on a scale
Standard Deviation 34.0

PRIMARY outcome

Timeframe: Day 0: no prosthesis (pre-fitting)

The Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire is a 30-item questionnaire that looks at the ability of a patient to perform certain upper extremity activities. This questionnaire is a self-report questionnaire that patients can rate difficulty and interference with daily life on a 5 point Likert scale. Scale Title: DASH Score. Scale Minimum: 0. Scale Maximum: 100. Higher score indicates worse outcome.

Outcome measures

Outcome measures
Measure
No Prosthesis, Then Prosthesis
n=11 Participants
Baseline outcome measurements will be performed without a prosthesis Outcome measurements will be performed after the subject has been fit with a prosthesis at 3 different points in time: immediately post-fitting, \~30 days post-fitting, and \~60 days post-fitting Point Digit: Patient is fit with Point Digit partial hand prosthetic system
Disability of the Arm, Shoulder and Hand (DASH)
29.8 score on a scale
Standard Deviation 14.6

PRIMARY outcome

Timeframe: Day 0: no prosthesis (pre-fitting)

The Southampton Hand Assessment Procedure (SHAP) is a clinically validated hand function test. Originally developed to assess the effectiveness of upper limb prostheses, the SHAP has now been applied to assessment of musculoskeletal and neurological conditions. Scale Title: Index of Function. Scale Minimum: 0. Scale Maximum: 100. Higher score indicates better outcome.

Outcome measures

Outcome measures
Measure
No Prosthesis, Then Prosthesis
n=11 Participants
Baseline outcome measurements will be performed without a prosthesis Outcome measurements will be performed after the subject has been fit with a prosthesis at 3 different points in time: immediately post-fitting, \~30 days post-fitting, and \~60 days post-fitting Point Digit: Patient is fit with Point Digit partial hand prosthetic system
Southampton Hand Assessment Procedure (SHAP)
70.9 score on a scale
Standard Deviation 29.5

PRIMARY outcome

Timeframe: Day 0: no prosthesis (pre-fitting)

Descriptive system for health-related quality of life states in adults, consisting of five dimensions (Mobility, Self-care, Usual activities, Pain \& discomfort, Anxiety \& depression), each of which has five severity levels that are described by statements appropriate to that dimension. Scale Title: EQ-5D-5L Score. Scale Minimum: 0. Scale Maximum: 100. Higher score indicates better outcome.

Outcome measures

Outcome measures
Measure
No Prosthesis, Then Prosthesis
n=11 Participants
Baseline outcome measurements will be performed without a prosthesis Outcome measurements will be performed after the subject has been fit with a prosthesis at 3 different points in time: immediately post-fitting, \~30 days post-fitting, and \~60 days post-fitting Point Digit: Patient is fit with Point Digit partial hand prosthetic system
EuroQol-5 Dimension (EQ-5D-5L)
84.5 score on a scale
Standard Deviation 12.5

PRIMARY outcome

Timeframe: Day 0: with prosthesis, immediately post-fitting

Capacity Assessment of Prosthetic Performance for the Upper Limb (CAPPFUL) provides a comprehensive, performance based measure for upper limb prosthetic use with any upper-limb functional prosthesis at any amputation level through assessment of commonplace activities that take place in various planes of movement. Scale Title: Overall Performance. Scale Minimum: 0. Scale Maximum: 100. Higher score indicates better outcome.

Outcome measures

Outcome measures
Measure
No Prosthesis, Then Prosthesis
n=11 Participants
Baseline outcome measurements will be performed without a prosthesis Outcome measurements will be performed after the subject has been fit with a prosthesis at 3 different points in time: immediately post-fitting, \~30 days post-fitting, and \~60 days post-fitting Point Digit: Patient is fit with Point Digit partial hand prosthetic system
Capacity Assessment of Prosthetic Performance for the Upper Limb (CAPPFUL)
84.0 scores on a scale
Standard Deviation 13.1

PRIMARY outcome

Timeframe: Day 0: with prosthesis, immediately post-fitting

The Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire is a 30-item questionnaire that looks at the ability of a patient to perform certain upper extremity activities. This questionnaire is a self-report questionnaire that patients can rate difficulty and interference with daily life on a 5 point Likert scale. Scale Title: DASH Score. Scale Minimum: 0. Scale Maximum: 100. Higher score indicates worse outcome.

Outcome measures

Outcome measures
Measure
No Prosthesis, Then Prosthesis
n=11 Participants
Baseline outcome measurements will be performed without a prosthesis Outcome measurements will be performed after the subject has been fit with a prosthesis at 3 different points in time: immediately post-fitting, \~30 days post-fitting, and \~60 days post-fitting Point Digit: Patient is fit with Point Digit partial hand prosthetic system
Disability of the Arm, Shoulder and Hand (DASH)
21.4 score on a scale
Standard Deviation 12.8

PRIMARY outcome

Timeframe: Day 0: with prosthesis, immediately post-fitting

The Southampton Hand Assessment Procedure (SHAP) is a clinically validated hand function test. Originally developed to assess the effectiveness of upper limb prostheses, the SHAP has now been applied to assessment of musculoskeletal and neurological conditions. Scale Title: Index of Function. Scale Minimum: 0. Scale Maximum: 100. Higher score indicates better outcome.

Outcome measures

Outcome measures
Measure
No Prosthesis, Then Prosthesis
n=11 Participants
Baseline outcome measurements will be performed without a prosthesis Outcome measurements will be performed after the subject has been fit with a prosthesis at 3 different points in time: immediately post-fitting, \~30 days post-fitting, and \~60 days post-fitting Point Digit: Patient is fit with Point Digit partial hand prosthetic system
Southampton Hand Assessment Procedure (SHAP)
69.9 score on a scale
Standard Deviation 20.7

PRIMARY outcome

Timeframe: Day 0: with prosthesis, immediately post-fitting

Descriptive system for health-related quality of life states in adults, consisting of five dimensions (Mobility, Self-care, Usual activities, Pain \& discomfort, Anxiety \& depression), each of which has five severity levels that are described by statements appropriate to that dimension. Scale Title: EQ-5D-5L Score. Scale Minimum: 0. Scale Maximum: 100. Higher score indicates better outcome.

Outcome measures

Outcome measures
Measure
No Prosthesis, Then Prosthesis
n=11 Participants
Baseline outcome measurements will be performed without a prosthesis Outcome measurements will be performed after the subject has been fit with a prosthesis at 3 different points in time: immediately post-fitting, \~30 days post-fitting, and \~60 days post-fitting Point Digit: Patient is fit with Point Digit partial hand prosthetic system
EuroQol-5 Dimension (EQ-5D-5L)
88.5 score on a scale
Standard Deviation 9.8

PRIMARY outcome

Timeframe: ~Day 30: with prosthesis, 30 days post-fitting

Capacity Assessment of Prosthetic Performance for the Upper Limb (CAPPFUL) provides a comprehensive, performance based measure for upper limb prosthetic use with any upper-limb functional prosthesis at any amputation level through assessment of commonplace activities that take place in various planes of movement. Scale Title: Overall Performance. Scale Minimum: 0. Scale Maximum: 100. Higher score indicates better outcome.

Outcome measures

Outcome measures
Measure
No Prosthesis, Then Prosthesis
n=11 Participants
Baseline outcome measurements will be performed without a prosthesis Outcome measurements will be performed after the subject has been fit with a prosthesis at 3 different points in time: immediately post-fitting, \~30 days post-fitting, and \~60 days post-fitting Point Digit: Patient is fit with Point Digit partial hand prosthetic system
Capacity Assessment of Prosthetic Performance for the Upper Limb (CAPPFUL)
86.8 scores on a scale
Standard Deviation 10.6

PRIMARY outcome

Timeframe: ~Day 30: with prosthesis, 30 days post-fitting

The Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire is a 30-item questionnaire that looks at the ability of a patient to perform certain upper extremity activities. This questionnaire is a self-report questionnaire that patients can rate difficulty and interference with daily life on a 5 point Likert scale. Scale Title: DASH Score. Scale Minimum: 0. Scale Maximum: 100. Higher score indicates worse outcome.

Outcome measures

Outcome measures
Measure
No Prosthesis, Then Prosthesis
n=11 Participants
Baseline outcome measurements will be performed without a prosthesis Outcome measurements will be performed after the subject has been fit with a prosthesis at 3 different points in time: immediately post-fitting, \~30 days post-fitting, and \~60 days post-fitting Point Digit: Patient is fit with Point Digit partial hand prosthetic system
Disability of the Arm, Shoulder and Hand (DASH)
16.0 score on a scale
Standard Deviation 9.9

PRIMARY outcome

Timeframe: ~Day 30: with prosthesis, 30 days post-fitting

The Southampton Hand Assessment Procedure (SHAP) is a clinically validated hand function test. Originally developed to assess the effectiveness of upper limb prostheses, the SHAP has now been applied to assessment of musculoskeletal and neurological conditions. Scale Title: Index of Function. Scale Minimum: 0. Scale Maximum: 100. Higher score indicates better outcome.

Outcome measures

Outcome measures
Measure
No Prosthesis, Then Prosthesis
n=11 Participants
Baseline outcome measurements will be performed without a prosthesis Outcome measurements will be performed after the subject has been fit with a prosthesis at 3 different points in time: immediately post-fitting, \~30 days post-fitting, and \~60 days post-fitting Point Digit: Patient is fit with Point Digit partial hand prosthetic system
Southampton Hand Assessment Procedure (SHAP)
74.9 score on a scale
Standard Deviation 23.3

PRIMARY outcome

Timeframe: ~Day 30: with prosthesis, 30 days post-fitting

Descriptive system for health-related quality of life states in adults, consisting of five dimensions (Mobility, Self-care, Usual activities, Pain \& discomfort, Anxiety \& depression), each of which has five severity levels that are described by statements appropriate to that dimension. Scale Title: EQ-5D-5L Score. Scale Minimum: 0. Scale Maximum: 100. Higher score indicates better outcome.

Outcome measures

Outcome measures
Measure
No Prosthesis, Then Prosthesis
n=11 Participants
Baseline outcome measurements will be performed without a prosthesis Outcome measurements will be performed after the subject has been fit with a prosthesis at 3 different points in time: immediately post-fitting, \~30 days post-fitting, and \~60 days post-fitting Point Digit: Patient is fit with Point Digit partial hand prosthetic system
EuroQol-5 Dimension (EQ-5D-5L)
89.2 score on a scale
Standard Deviation 8.5

PRIMARY outcome

Timeframe: ~Day 60: with prosthesis, 60 days post-fitting

Capacity Assessment of Prosthetic Performance for the Upper Limb (CAPPFUL) provides a comprehensive, performance based measure for upper limb prosthetic use with any upper-limb functional prosthesis at any amputation level through assessment of commonplace activities that take place in various planes of movement. Scale Title: Overall Performance. Scale Minimum: 0. Scale Maximum: 100. Higher score indicates better outcome.

Outcome measures

Outcome measures
Measure
No Prosthesis, Then Prosthesis
n=11 Participants
Baseline outcome measurements will be performed without a prosthesis Outcome measurements will be performed after the subject has been fit with a prosthesis at 3 different points in time: immediately post-fitting, \~30 days post-fitting, and \~60 days post-fitting Point Digit: Patient is fit with Point Digit partial hand prosthetic system
Capacity Assessment of Prosthetic Performance for the Upper Limb (CAPPFUL)
91.0 scores on a scale
Standard Deviation 8.1

PRIMARY outcome

Timeframe: ~Day 60: with prosthesis, 60 days post-fitting

The Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire is a 30-item questionnaire that looks at the ability of a patient to perform certain upper extremity activities. This questionnaire is a self-report questionnaire that patients can rate difficulty and interference with daily life on a 5 point Likert scale. Scale Title: DASH Score. Scale Minimum: 0. Scale Maximum: 100. Higher score indicates worse outcome.

Outcome measures

Outcome measures
Measure
No Prosthesis, Then Prosthesis
n=11 Participants
Baseline outcome measurements will be performed without a prosthesis Outcome measurements will be performed after the subject has been fit with a prosthesis at 3 different points in time: immediately post-fitting, \~30 days post-fitting, and \~60 days post-fitting Point Digit: Patient is fit with Point Digit partial hand prosthetic system
Disability of the Arm, Shoulder and Hand (DASH)
15.5 score on a scale
Standard Deviation 10.5

PRIMARY outcome

Timeframe: ~Day 60: with prosthesis, 60 days post-fitting

The Southampton Hand Assessment Procedure (SHAP) is a clinically validated hand function test. Originally developed to assess the effectiveness of upper limb prostheses, the SHAP has now been applied to assessment of musculoskeletal and neurological conditions. Scale Title: Index of Function. Scale Minimum: 0. Scale Maximum: 100. Higher score indicates better outcome.

Outcome measures

Outcome measures
Measure
No Prosthesis, Then Prosthesis
n=11 Participants
Baseline outcome measurements will be performed without a prosthesis Outcome measurements will be performed after the subject has been fit with a prosthesis at 3 different points in time: immediately post-fitting, \~30 days post-fitting, and \~60 days post-fitting Point Digit: Patient is fit with Point Digit partial hand prosthetic system
Southampton Hand Assessment Procedure (SHAP)
75.3 score on a scale
Standard Deviation 21.2

PRIMARY outcome

Timeframe: ~Day 60: with prosthesis, 60 days post-fitting

Descriptive system for health-related quality of life states in adults, consisting of five dimensions (Mobility, Self-care, Usual activities, Pain \& discomfort, Anxiety \& depression), each of which has five severity levels that are described by statements appropriate to that dimension. Scale Title: EQ-5D-5L Score. Scale Minimum: 0. Scale Maximum: 100. Higher score indicates better outcome.

Outcome measures

Outcome measures
Measure
No Prosthesis, Then Prosthesis
n=11 Participants
Baseline outcome measurements will be performed without a prosthesis Outcome measurements will be performed after the subject has been fit with a prosthesis at 3 different points in time: immediately post-fitting, \~30 days post-fitting, and \~60 days post-fitting Point Digit: Patient is fit with Point Digit partial hand prosthetic system
EuroQol-5 Dimension (EQ-5D-5L)
90.1 score on a scale
Standard Deviation 8.7

Adverse Events

No Prosthesis, Then Prosthesis

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Director of Clinical Research

Point Designs

Phone: 7206004753

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place