Comparison of Cardiopulmonary Fitness Level With Normal Values After COVID-19
NCT ID: NCT04753346
Last Updated: 2023-12-15
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
240 participants
OBSERVATIONAL
2021-02-15
2024-01-01
Brief Summary
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Detailed Description
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Patients older than 18 years old who are diagnosed with COVID-19 according to clinical symptoms and rt-PCR test positivity and at least 30 days past the end of their symptoms are accepted for the study.
According to World Health Organization's (WHO) classification, COVID-19 disease severity is determined. Physical activity level of the patients before COVID-19 is evaluated with International Physical Activity Questionnaire. Risk of anxiety and depression of the patients is identified with Hospital Anxiety and Depression Scale (HADS), which has 14 questions. To evaluate cardiopulmonary fitness level, cardiopulmonary exercise test (CPET) and 6-minute walk test are applied. Cardiopulmonary exercise test is gold standard to determine cardiac and respiratory functions. Pulmonary function test is performed to identify the conditions that affect the results of cardiopulmonary exercise test.
Conditions
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Keywords
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Study Design
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OTHER
CROSS_SECTIONAL
Study Groups
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Mild Disease
Symptomatic patients meeting the case definition for COVID-19 without evidence of viral pneumonia or hypoxia.
Physical Activity Level
International Physical Activity Questionnaire
Anxiety and Depression Assessment
Hospital Anxiety and Depression Scale
Exercise Capacity
6 Minute Walk Test
Pulmonary Function Test
Spirometry
Cardiopulmonary Fitness Level
Cardiopulmonary Exercise Test
Cognitive Assessment
Montreal Cognitive Assessment
Pneumonia
Patients with clinical signs of pneumonia (fever, cough, dyspnoea, fast breathing) but no signs of severe pneumonia, including SpO2 ≥ 90% on room air
Physical Activity Level
International Physical Activity Questionnaire
Anxiety and Depression Assessment
Hospital Anxiety and Depression Scale
Exercise Capacity
6 Minute Walk Test
Pulmonary Function Test
Spirometry
Cardiopulmonary Fitness Level
Cardiopulmonary Exercise Test
Cognitive Assessment
Montreal Cognitive Assessment
Severe Pneumonia
Patients with clinical signs of pneumonia (fever, cough, dyspnoea,fast breathing) plus one of the following: respiratory rate \> 30 breaths/min; severe respiratory distress; or SpO2 \< 90% on room air.
Physical Activity Level
International Physical Activity Questionnaire
Anxiety and Depression Assessment
Hospital Anxiety and Depression Scale
Exercise Capacity
6 Minute Walk Test
Pulmonary Function Test
Spirometry
Cardiopulmonary Fitness Level
Cardiopulmonary Exercise Test
Cognitive Assessment
Montreal Cognitive Assessment
Critical Disease
Patients have one of the following: acute respiratory distress syndrome; sepsis; or septic shock.
Physical Activity Level
International Physical Activity Questionnaire
Anxiety and Depression Assessment
Hospital Anxiety and Depression Scale
Exercise Capacity
6 Minute Walk Test
Pulmonary Function Test
Spirometry
Cardiopulmonary Fitness Level
Cardiopulmonary Exercise Test
Cognitive Assessment
Montreal Cognitive Assessment
Interventions
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Physical Activity Level
International Physical Activity Questionnaire
Anxiety and Depression Assessment
Hospital Anxiety and Depression Scale
Exercise Capacity
6 Minute Walk Test
Pulmonary Function Test
Spirometry
Cardiopulmonary Fitness Level
Cardiopulmonary Exercise Test
Cognitive Assessment
Montreal Cognitive Assessment
Eligibility Criteria
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Inclusion Criteria
* It must have been at least 30 days after symptoms of COVID-19 improved.
Exclusion Criteria
* Unstable angina
* Active endocarditis, myocarditis or pericarditis
* Symptomatic severe aortic stenosis
* Uncontrolled heart failure
* Acute pulmonary embolus, pulmonary infarction or thrombosis of lower extremities
* Suspected dissecting aneurysm
* Uncontrolled asthma
* Room air desaturation at rest (O2 ⩽85%)
* Respiratory failure
* Acute non-cardiopulmonary disorder that may affect exercise performance or be aggravated by exercise
* Mental impairment
* Severe untreated arterial hypertension at rest (\>200 mm Hg systolic, \>120 mm Hg diastolic)
* High-degree atrioventricular block
* Orthopaedic, neurological or systemic impairments that leading to inability to perform test
18 Years
ALL
No
Sponsors
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Ankara University
OTHER
Responsible Party
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Burak Kamil Turan
MD
Locations
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Ankara University, Faculty of Medicine, Physical Medicine and Rehabilitation Department
Ankara, , Turkey (Türkiye)
Countries
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Central Contacts
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Facility Contacts
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Burak K Turan
Role: primary
Other Identifiers
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I11-670-20
Identifier Type: -
Identifier Source: org_study_id