Clinical Characteristics of Patients With Leukemia and COVID-19

NCT ID: NCT04745416

Last Updated: 2021-02-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-01-01

Study Completion Date

2021-01-25

Brief Summary

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The purpose of this study is to describe the main clinical characteristics of patients with de novo acute lymphoblastic leukemia treated inside the third level hospitals converted to Coronavirus disease 2019 (COVID-19) attention for the metropolitan area of Mexico City.

Detailed Description

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Retrospective, observational study in patients with diagnosis of acute lymphoblastic leukemia, according to the criteria of the World Health Organization, from April 2020 to December 2020. Patients was cared for in the hematology department of the Hospital Regional de Alta Especialidad de Ixtapaluca or the Hospital General de México. Both hospitals have been assigned as Coronavirus disease 2019 (COVID-19) hospitals, limiting the access, number of outpatient visits and chemotherapy protocols.

Real-time polymerase chain reaction (RT-PCR) test for Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was performed for patients with respiratory symptoms or history of contact with suspected / confirmed cases of COVID-19 Upon having a positive RT-PCR test, patients were transferred to a respiratory isolation unit to continue their recovery. Support treatment for COVID-19 was based on local considerations.

Conditions

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Leukemia, Acute Covid19 Leukemia, Lymphoblastic

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Leukemia and COVID-19

Patients diagnosed with acute lymphoblastic leukemia according to the criteria of the World Health Organization and confirmed diagnosis of COVID-19 by RT-PCR test

No interventions assigned to this group

Leukemia

Patients diagnosed with acute lymphoblastic leukemia according to the criteria of the World Health Organization without suspicion of COVID-19

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Patients with diagnosis of acute lymphoblastic leukemia according to the criteria of the World Health Organization.

Exclusion Criteria

* Age less than 18 years
* Incomplete medical records
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hospital General de Mexico

OTHER_GOV

Sponsor Role lead

Responsible Party

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Christian Omar Ramos-Peñafiel, MD, PhD

Head of the hematology hospitalization area

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Hospital Regional de Alta Especialidad de Ixtapaluca

Ixtapaluca, State of Mexico, Mexico

Site Status

Hospital General de México "Dr. Eduardo Liceaga"

Mexico City, , Mexico

Site Status

Countries

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Mexico

Other Identifiers

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DECS/JPO-CT-400-2020

Identifier Type: -

Identifier Source: org_study_id

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