CONtrolled Focal Fibrous Band Release Method Study

NCT ID: NCT04743635

Last Updated: 2023-06-06

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

74 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-01-07

Study Completion Date

2022-03-04

Brief Summary

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Study to evaluate the safety and effectiveness of the Avéli medical device to reduce the appearance of cellulite.

Detailed Description

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Multi-center, single-arm clinical study to evaluate the safety and effectiveness of the Avéli device in reducing the appearance of cellulite.

Conditions

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Cellulite

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

All participants were treated with the Avéli device.
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Targeted Verifiable Subcision (TVS) with the Avéli device, mITT

Modified intent to treat population (n=68). The modified intent to treat population was used to evaluate effectiveness.

The single procedure was conducted using the Avéli device for TVS. Cellulite can be treated on the thighs and buttocks

Group Type EXPERIMENTAL

Avéli device

Intervention Type DEVICE

Minimally invasive single procedure with the Avéli device for reduction in the appearance of cellulite in the thighs and buttocks.

Targeted Verifiable Subcision (TVS) with the Avéli device, Roll-in

The roll-in population (n=6) was excluded from the effectiveness analyses. For Investigators that have not previously performed an Avéli procedure, two (2) participants were classified as roll-in participants. The single procedure was conducted using the Avéli device for TVS. Cellulite can be treated on the thighs and buttocks

Group Type EXPERIMENTAL

Avéli device

Intervention Type DEVICE

Minimally invasive single procedure with the Avéli device for reduction in the appearance of cellulite in the thighs and buttocks.

Interventions

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Avéli device

Minimally invasive single procedure with the Avéli device for reduction in the appearance of cellulite in the thighs and buttocks.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Moderate to severe cellulite

Exclusion Criteria

* Body Mass Index ≥30.0
Minimum Eligible Age

21 Years

Maximum Eligible Age

55 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Revelle Aesthetics, Inc

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Dr. G. William Stevens, MD

Role: PRINCIPAL_INVESTIGATOR

Marina Plastic Surgery

Locations

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Clinical Site #3

Los Angeles, California, United States

Site Status

Clinical Site #5

San Diego, California, United States

Site Status

Clinical Site #4

San Francisco, California, United States

Site Status

Clinical Site #2

Coral Gables, Florida, United States

Site Status

Clinical Site #6

Shreveport, Louisiana, United States

Site Status

Clinical Site #8

Chestnut Hill, Massachusetts, United States

Site Status

Clinical Site #1

Minneapolis, Minnesota, United States

Site Status

Clinical Site #7

Southport, Queensland, Australia

Site Status

Clinical Site #9

Toowoomba, Queensland, Australia

Site Status

Countries

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United States Australia

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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CP-10472

Identifier Type: -

Identifier Source: org_study_id

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