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TREAT Child Alcohol Use Disorder (C-AUD) in Eastern Uganda

NCT ID: NCT04743024

Last Updated: 2023-12-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

7188 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-12-27

Study Completion Date

2025-07-31

Brief Summary

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The investigators will investigate the existence of alcohol drinking among children living under adult supervision and care, living within the communities. The investigators will focus on the age group 6-13 years overlapping with the recommended age for primary school attendance. The project is approaching the research topic using quantitative and qualitative methods. The TREAT C-AUD research project will therefore document to which degree alcohol drinking is a problem among children in Mbale, Eastern Uganda.

Detailed Description

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Uganda has as many other sub-Saharan countries high alcohol consumption per capita and traditions for home brewing. The TREAT C-AUD research project, with partners from Makerere University in Uganda, University of Bergen and Norwegian University of Science and Technology in Norway, will investigate the existence of alcohol drinking among children living under adult supervision and care, living within the communities. The investigators will focus on the age group 6-13 years overlapping with the recommended age for primary school attendance. The project is approaching the research topic from comprehensive perspectives including a large cross-sectional study, interviews with parents and carers, children and stakeholders in the communities, schools and in the health system. The investigators have been including community representatives, expert groups, user groups and stakeholders in the development of screening tools and will do so in interpreting and disseminating the results. The investigators have to take the Covid-19 situation into account both with regard to its effect on the research question at stake and the methods used. The TREAT C-AUD research project will therefore document to which degree alcohol drinking is a problem among children in the communities in Mbale District, Eastern Ugandan. The data collection is capturing cofactors such as other substance use, mental health, parenting, trauma, nutrition and growth. The development of alcohol assessment tools can be used by the health- and school-system for detection and handling of children having problems with alcohol. The investigators will collaborate closely with services in case of identification of children suffering severe harm and adhere to Good Clinical Practice guidelines for ethical conduct, the consent procedure, follow-up and referral.

Conditions

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Alcohol Abuse Alcohol Drinking Alcoholism Alcohol Use Disorder Alcohol Dependence Child Abuse Child Malnutrition Child Neglect Child Mental Disorder Child, Only

Study Design

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Observational Model Type

ECOLOGIC_OR_COMMUNITY

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Household

Household carer-child pairs will be included according to age and consent criteria

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

Care-giver- child pairs

* Children 6-13 years
* Caregiver of eligible child
* Caregiver adult capable of giving informed consent
* Living in household for minimum 6 months together

Exclusion Criteria

• Caregiver or child not living in household
Minimum Eligible Age

6 Years

Maximum Eligible Age

13 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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The Research Council of Norway

OTHER

Sponsor Role collaborator

Makerere University

OTHER

Sponsor Role collaborator

Norwegian University of Science and Technology

OTHER

Sponsor Role collaborator

University of Bergen

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Guri Rørtveit, PhD

Role: STUDY_CHAIR

Leader

Locations

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School of Public Health, Makerere University

Kampala, , Uganda

Site Status RECRUITING

Countries

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Uganda

Central Contacts

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Ingunn MS Engebretsen, PhD

Role: CONTACT

Phone: +4755588553

Email: [email protected]

Anne-Berit Kolmanskolg, Ms

Role: CONTACT

Phone: +47 55 58 54 39

Email: [email protected]

Facility Contacts

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Juliet N Babirye, PhD

Role: primary

Esther Buregyeya, PhD

Role: backup

References

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Engebretsen IMS, Nalugya JS, Skylstad V, Ndeezi G, Akol A, Babirye JN, Nankabirwa V, Tumwine JK. "I feel good when I drink"-detecting childhood-onset alcohol abuse and dependence in a Ugandan community trial cohort. Child Adolesc Psychiatry Ment Health. 2020 Oct 24;14:42. doi: 10.1186/s13034-020-00349-z. eCollection 2020.

Reference Type RESULT
PMID: 33110445 (View on PubMed)

Akol A, Makumbi F, Babirye JN, Nalugya JS, Nshemereirwe S, Engebretsen IMS. Does mhGAP training of primary health care providers improve the identification of child- and adolescent mental, neurological or substance use disorders? Results from a randomized controlled trial in Uganda. Glob Ment Health (Camb). 2018 Sep 10;5:e29. doi: 10.1017/gmh.2018.18. eCollection 2018.

Reference Type RESULT
PMID: 30455964 (View on PubMed)

Akol A, Nalugya J, Nshemereirwe S, Babirye JN, Engebretsen IMS. Does child and adolescent mental health in-service training result in equivalent knowledge gain among cadres of non-specialist health workers in Uganda? A pre-test post-test study. Int J Ment Health Syst. 2017 Aug 24;11:50. doi: 10.1186/s13033-017-0158-y. eCollection 2017.

Reference Type RESULT
PMID: 28855962 (View on PubMed)

Skylstad V, Aber H, Bakken V, Dierkes J, Iversen SA, Kisaakye E, Kuhl MJ, Nalugya JS, Rayamajhi D, Sebuwufu D, Skar AS, Skokauskas N, Valeckaite N, Wamani H, S Engebretsen IM, Babirye JN; TREAT C-AUD consortium. Child alcohol use disorder in Eastern Uganda: screening, diagnostics, risk factors and management of children drinking alcohol in Uganda (TREAT C-AUD): a mixed-methods research protocol. BMJ Paediatr Open. 2021 Jul 28;5(1):e001214. doi: 10.1136/bmjpo-2021-001214. eCollection 2021.

Reference Type DERIVED
PMID: 34345718 (View on PubMed)

Study Documents

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Document Type: Study Protocol

View Document

Related Links

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https://www.uib.no/en/rg/gmh/134660/treat-c-aud-project-page

University home page

Other Identifiers

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RCN project no 285489

Identifier Type: -

Identifier Source: org_study_id