Epidural Block Impairs HPV During One-lung Ventilation: an EIT- Based Prospective Observation Study
NCT ID: NCT04730089
Last Updated: 2021-01-29
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
50 participants
OBSERVATIONAL
2020-08-01
2022-07-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
PROSPECTIVE
Interventions
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Electrical impedance tomography
A bolus of 10ml 10% NaCl was injected during a respiratory pause (≥10s) through the central venous catheter.The results of arterial blood gas analysis and the data of EIT were collected before the first prone session (time baseline), the end of prone positioning (time P).
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
Contraindications of PulmoVista 500:
Patients with pacemakers, defibrillators or other electrically active implants Patients with damaged skin or impaired skin contact of the electrodes due to wound dressings Patients where the attachment of the patient belt could pose a risk to the patient, e.g. patients with spinal lesions or fractures Patients with uncontrolled body movements Extremely obese patients (BMI\>50) Patients during pregnancy Patients with massive lung edema Use during electricity-based therapies, such as electrosurgery or electrocautery Use in the presence of strong magnetic fields Use in conjunction with other bioimpedance measurement devices
18 Years
80 Years
ALL
No
Sponsors
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Shanghai Zhongshan Hospital
OTHER
Responsible Party
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Ming Zhong
Professor
Principal Investigators
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Ming Zhong, MD, phD
Role: PRINCIPAL_INVESTIGATOR
Fudan University
Locations
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Zhongshan Hospital of Fudan University
Shanghai, Shanghai Municipality, China
Countries
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Central Contacts
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Facility Contacts
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Ming Zhong, MD, phD
Role: primary
Yuxian Wang, BSc
Role: backup
References
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Wang Y, Wei Y, Chen G, Wang Z, Fan Y, Wang J, Yang Y, Zhou D, Zhong M. The effects of thoracic epidural blockade on ventilation-perfusion matching during one-lung ventilation: An exploratory study. J Clin Anesth. 2024 Dec;99:111678. doi: 10.1016/j.jclinane.2024.111678. Epub 2024 Nov 6.
Other Identifiers
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EB-EIT
Identifier Type: -
Identifier Source: org_study_id