The Need of Revisiting to an Outpatient Clinic After the Prescription of Vonoprazan or Esomeprazole

NCT ID: NCT04720781

Last Updated: 2025-05-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

300 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-01-21

Study Completion Date

2024-12-31

Brief Summary

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After vonoprazan (20mg/day) or esomeprazole (20mg/day) for 4weeks is prescribed for patients with erosive esophagitis diagnosed by esophagogastroduodenoscopy, the number of patients who will visit our outpatient clinic again due to some reasons without any appointments is compared with vonoprazan group and esomeprazole.

Detailed Description

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1. Patients who have erosive esophagitis diagnosed by esophagogastroduodenoscopy is enrolled.
2. Vonoprazan (20mg/day) or esomeprazole (20mg/day) is prescribed for 4weeks the patients randomly without next appointments.
3. Some patients may visit our outpatient clinic again due to some reasons without any appointments.
4. The number of the patients who revisit our outpatient clinic again is compared with vonoprazan group and esomeprazole.

Conditions

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Gastroesophageal Reflux

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Vonoprazan

Vonoprazan (20mg/day) is prescribed for patients with erosive esophagitis

Group Type ACTIVE_COMPARATOR

Vonoprazan

Intervention Type DRUG

Vonoprazan (20mg/day) is prescribed for 4 weeks.

Esomeprazole

Esomeprazole (20mg/day) is prescribed for patients with erosive esophagitis

Group Type PLACEBO_COMPARATOR

Esomeprazole

Intervention Type DRUG

esomeprazole (20mg/day)

Interventions

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Vonoprazan

Vonoprazan (20mg/day) is prescribed for 4 weeks.

Intervention Type DRUG

Esomeprazole

esomeprazole (20mg/day)

Intervention Type DRUG

Other Intervention Names

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Esomeprazole

Eligibility Criteria

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Inclusion Criteria

* outpatients belonging to American Society of Anesthesiologists class I or II
* patients have erosive esophagitis diagnosed by esophagogastroduodenoscopy shortly before the prescription

Exclusion Criteria

* other acid blockers are taken
Minimum Eligible Age

19 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Showa Inan General Hospital

OTHER

Sponsor Role lead

Responsible Party

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Akira Horiuchi

Chief of Digestive Disease Center

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Showa Inan General hospital

Komagane, Nagano, Japan

Site Status

Countries

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Japan

Other Identifiers

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Revisiting

Identifier Type: -

Identifier Source: org_study_id

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