Trial Outcomes & Findings for Evaluating Mindfulness-Based Interventions With New Fibromyalgia Patients (NCT NCT04720053)

NCT ID: NCT04720053

Last Updated: 2024-09-03

Results Overview

Wide pain index (WPI) defined as a 4-quadrant plus axial pain, measuring widespread pain in 19 body areas where the patient feels pain over the prior week. Each area identified on the list counts as 1. The range on the WPI score can range from 0 to 19. With lower number indicating fewer areas of pain (hence lower pain). The difference is calculated by taking the baseline score minus the end of treatment score.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

41 participants

Primary outcome timeframe

Baseline to end of treatment (day 90)

Results posted on

2024-09-03

Participant Flow

Potential participants were patients diagnosed with fibromyalgia at a large healthcare facility in the Midwestern United States. Enrollment took place from November 01, 2021 to January 27, 2023. Study participation concluded on July 28, 2023.

After consent, one participant was found not to meet study entry criteria (no mobile device) and had to be removed from study.

Participant milestones

Participant milestones
Measure
Wearable Brain Sensing Wellness Device Headband System
Subject diagnosed with fibromyalgia at Mayo Clinic GIM Fibromyalgia Clinic will receive a wearable brain sensing wellness device headband system, and will be given a demonstration of the mindfulness sessions, with detailed instructions on how to begin each session. Wearable brain sensing wellness device headband system: Brain sensing headband that measures brain activity by detecting electrical impulses created by the brain.
Overall Study
STARTED
40
Overall Study
COMPLETED
28
Overall Study
NOT COMPLETED
12

Reasons for withdrawal

Reasons for withdrawal
Measure
Wearable Brain Sensing Wellness Device Headband System
Subject diagnosed with fibromyalgia at Mayo Clinic GIM Fibromyalgia Clinic will receive a wearable brain sensing wellness device headband system, and will be given a demonstration of the mindfulness sessions, with detailed instructions on how to begin each session. Wearable brain sensing wellness device headband system: Brain sensing headband that measures brain activity by detecting electrical impulses created by the brain.
Overall Study
Lost to Follow-up
12

Baseline Characteristics

Evaluating Mindfulness-Based Interventions With New Fibromyalgia Patients

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Wearable Brain Sensing Wellness Device Headband System
n=40 Participants
Subject diagnosed with fibromyalgia at Mayo Clinic GIM Fibromyalgia Clinic will receive a wearable brain sensing wellness device headband system, and will be given a demonstration of the mindfulness sessions, with detailed instructions on how to begin each session. Wearable brain sensing wellness device headband system: Brain sensing headband that measures brain activity by detecting electrical impulses created by the brain.
Age, Continuous
40 years
STANDARD_DEVIATION 15 • n=5 Participants
Sex/Gender, Customized
male
6 Participants
n=5 Participants
Sex/Gender, Customized
female
33 Participants
n=5 Participants
Sex/Gender, Customized
other
1 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
2 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
38 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants
n=5 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=5 Participants
Race (NIH/OMB)
Asian
0 Participants
n=5 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=5 Participants
Race (NIH/OMB)
Black or African American
0 Participants
n=5 Participants
Race (NIH/OMB)
White
40 Participants
n=5 Participants
Race (NIH/OMB)
More than one race
0 Participants
n=5 Participants
Race (NIH/OMB)
Unknown or Not Reported
0 Participants
n=5 Participants

PRIMARY outcome

Timeframe: Baseline to end of treatment (day 90)

Population: Those with complete data at both baseline and end of treatment (day 90)

Wide pain index (WPI) defined as a 4-quadrant plus axial pain, measuring widespread pain in 19 body areas where the patient feels pain over the prior week. Each area identified on the list counts as 1. The range on the WPI score can range from 0 to 19. With lower number indicating fewer areas of pain (hence lower pain). The difference is calculated by taking the baseline score minus the end of treatment score.

Outcome measures

Outcome measures
Measure
Wearable Brain Sensing Wellness Device Headband System
n=28 Participants
Subject diagnosed with fibromyalgia at Mayo Clinic GIM Fibromyalgia Clinic will receive a wearable brain sensing wellness device headband system, and will be given a demonstration of the mindfulness sessions, with detailed instructions on how to begin each session. Wearable brain sensing wellness device headband system: Brain sensing headband that measures brain activity by detecting electrical impulses created by the brain.
Change in Widespread Pain Index (WPI)
1.4 units on a scale
Standard Deviation 2.8

PRIMARY outcome

Timeframe: Baseline to end of treatment (day 90)

Population: Participants with measurements at both baseline and end of treatment (day 90)

Measured on a 0-10 pain assessment scale. Participants rate their stress on a scale of 0 to 10. Zero means "no stress," and 10 means "the worst possible stress". The difference is calculated by taking the baseline score minus the end of treatment score.

Outcome measures

Outcome measures
Measure
Wearable Brain Sensing Wellness Device Headband System
n=30 Participants
Subject diagnosed with fibromyalgia at Mayo Clinic GIM Fibromyalgia Clinic will receive a wearable brain sensing wellness device headband system, and will be given a demonstration of the mindfulness sessions, with detailed instructions on how to begin each session. Wearable brain sensing wellness device headband system: Brain sensing headband that measures brain activity by detecting electrical impulses created by the brain.
Change in Perceived Stress Scale
4.1 units on a scale
Standard Deviation 6.04

Adverse Events

Wearable Brain Sensing Wellness Device Headband System

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr. Sanjeev Nanda

Mayo Clinic

Phone: 507-284-9919

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place