PrevA Study - Evaluation of an App-based Nutritional Concept

NCT ID: NCT04717076

Last Updated: 2022-03-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-04-12

Study Completion Date

2021-10-12

Brief Summary

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The PrevA study is designed to evaluate our developed nutritional concept to implement a heart healthy diet. The nutritional concept based on nutrient-optimized daily menu plans for each study day. The plans are personalized according to participants age, gender, and level of physical activity. The PrevA study consists of four periods differing in the energy intake specified by the menu plans.

The study is carried out in a 4-armed parallel design. In group 1, the participants receive the individualized daily plans via the app coupled with the smartwatch to record participants physical activity and heart rate. Groups 2 and 3 receive a printed version of the daily plans with or without personal nutritional advice. The fourth group serves as a control group, which receives general nutritional recommendations but no daily menu plans. During this time, blood samples and urine are collected every four weeks to analyze the study parameters.

Detailed Description

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Smartphone-based communication technologies are developing rapidly, and the number of so-called mobile health applications is rising. The number of validated and scientifically tested offers is comparatively small. To address this weak point, we developed a personalized nutritional concept to implement a heart-healthy diet. In cooperation with the Preventicus GmbH, Jena, the concept was integrated in an App-based tool. In addition, the app relates to a smartwatch to encourage and track physical activity. The PrevA study will be conducted to evaluate the overall concept.

The nutritional concept based on nutrient-optimized daily menu plans for each study day. The plans are personalized according to participants age, gender, and level of physical activity.

The study is carried out in a 4-armed parallel design. In group 1, the participants receive the individualized daily plans via the app coupled with the smartwatch to record participants physical activity and heart rate. Groups 2 and 3 receive a printed version of the daily plans with or without personal nutritional advice. The fourth group serves as a control group, which receives general nutritional recommendations but no daily menu plans.

In groups 1 to 3, the daily plans are issued in 4 energy levels. At the beginning, the test subjects receive daily plans according to the recommendations for energy intake of the German Nutrition Society (DGE), adapted to their age, gender, and activity level (level 1). After four study weeks, the energy content of the plans is reduced to 85% of the energy intake recommended by the DGE (level 2) and after further four weeks of the PrevA study the energy level is reduced to 70% of the energy intake recommended by the DGE (level 3). Level 4 serves as a stabilization phase and provides the energy content of level 1. The study period extends over a total of 16 study weeks. During this time, blood samples and urine are collected every four weeks to analyze the study parameters. In addition, anthropometric data, data on personal health status and cardiovascular risk profile are assessed.

Conditions

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Reduction of Cardiovascular Risk Factors

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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App-based nutritional concept and fitness tracking

App-based nutritional concept and fitness tracking

Group Type ACTIVE_COMPARATOR

App-based nutritional concept and fitness tracking

Intervention Type BEHAVIORAL

The App-based nutritional concept based on menu plan, which are personalized according to participants age, gender, physical activity. The App is coupled with a Smartwatch to encourage and track physical activity over the study period.

Nutritional concept with individual nutritional counselling

Nutritional concept with individual nutritional counselling

Group Type EXPERIMENTAL

Nutritional concept with individual nutritional counselling

Intervention Type BEHAVIORAL

Nutritional concept based on personalized menu plans and individual nutritional counselling every four weeks (4 times during the study)

Nutritional concept without individual nutritional counselling

Nutritional concept without individual nutritional counselling

Group Type EXPERIMENTAL

Nutritional concept without individual nutritional counselling

Intervention Type BEHAVIORAL

Nutritional concept based on personalized menu plans

Control group

Control group - no intervention

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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App-based nutritional concept and fitness tracking

The App-based nutritional concept based on menu plan, which are personalized according to participants age, gender, physical activity. The App is coupled with a Smartwatch to encourage and track physical activity over the study period.

Intervention Type BEHAVIORAL

Nutritional concept with individual nutritional counselling

Nutritional concept based on personalized menu plans and individual nutritional counselling every four weeks (4 times during the study)

Intervention Type BEHAVIORAL

Nutritional concept without individual nutritional counselling

Nutritional concept based on personalized menu plans

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Voluntary participation with documented informed consent
* Willingness and ability to adhere to the study protocol
* Males / female) aged ≥ 20 years and ≤ 51 years
* BMI: ≥ 25 ≤ 35 kg / m2 (obesity grade 1)
* Owning a smartphone (android)
* no or moderate alcohol consumption (≤ 2 glasses / week)
* non-smoker (if possible)

Exclusion Criteria

Comorbidities:

* Hypercholesterolemia (genetic defect / familial predisposition)
* Diabetes mellitus type 1 or 2
* Thyroid dysfunction (hyper- or hypothyroidism)
* Food intolerance / allergies to ingredients in the study foods
* Medications: lipid-lowering drugs, glucocorticoids
* Dietary supplements: especially n-3 fatty acids, vitamin E.
* Extremely high physical activity (daily)
* Alcohol abuse (daily)
* (smoker) \[if there are not enough test persons available, \> 7 smokers should be included so that a statistical analysis is possible\]
* Uncontrolled organic diseases
* Alcohol, drug or drug abuse
* Participation in other clinical observational studies during or 4 weeks. before starting this study
* Serious behavioral problems, emotional problems or psychiatric problems which the investigator believes would lead to a lack of compliance
* Pregnancy, breastfeeding and unsafe contraception
* Other reasons that are considered important by the investigator
Minimum Eligible Age

20 Years

Maximum Eligible Age

69 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Jena

OTHER

Sponsor Role lead

Responsible Party

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Christine Dawczynski,PhD

PhD, Head of Junior Research Group Nutritional Concepts, University of Jena

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Christine Dawczynski, PhD

Role: PRINCIPAL_INVESTIGATOR

Friedrich-Schiller-University

Locations

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Friedrich-Schiller University

Jena, Thuringia, Germany

Site Status

Countries

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Germany

Other Identifiers

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H11_21

Identifier Type: -

Identifier Source: org_study_id

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