Comparative Clinical Effects of Salvadora Persica Oral Rinse And A Phenolic Commercial Mouth Wash On Human Oral Health

NCT ID: NCT04713566

Last Updated: 2021-01-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-03-01

Study Completion Date

2021-09-30

Brief Summary

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ABSTRACT:

OBJECTIVE: To compare the clinical effects of Salvadora persica (miswak) oral rinse and commercial Listerein mouth wash on oral health of socially deprived madrasa girls.

METHODS: Girls aged 18-22 years living permanently in a madrasa of Multan city will be recruited. Sample size and trial duration will be determined using the American Dental Association guidelines. Participants will be randomized into two interventional groups; A and B and will be either provided with Salvadora persica oral rinse and commercial Listerein mouth wash respectively. Pre, mid and post-intervention examinations will be executed by a blind and calibrated examiner using Turesky Quigley Hein Plaque and Loe and Silness Gingival indices. Statistical analysis will include descriptive statistics and two sample independent t-tests. The p-value of \<0.05 will be considered significant at 95 % confidence level.

KEY WORDS: Dental plaque, Gingivitis, Miswak, Mouthwash

Detailed Description

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Comparative clinical effects of Salvadora persica (miswak) oral rinse and commercial Listerein mouth wash will be studied on the oral health of socially deprived madrasa girls. Girls aged 18-22 years living permanently in a madrasa of Multan city will be recruited. Sample size and trial duration will be determined using the American Dental Association guidelines. Participants will be randomized into two interventional groups; A and B and were either provided with Salvadora persica oral rinse and commercial Listerein mouth wash respectively. Pre, mid and post-intervention examinations will be executed by a blind and calibrated examiner using Turesky Quigley Hein Plaque and Loe and Silness Gingival indices. Statistical analysis will include descriptive statistics and two sample independent t-tests. The p-value of \<0.05 will be considered significant at 95 % confidence level.

Conditions

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Plaque, Dental

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

TRIPLE

Participants Caregivers Outcome Assessors

Study Groups

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Group A

will be using Salvadora Persica oral rinse

Group Type EXPERIMENTAL

oral rinces

Intervention Type OTHER

natural and commercial oral rinses were compared for efficacy

Group B

will be using Commercial Phenolic mouthwash.

Group Type EXPERIMENTAL

oral rinces

Intervention Type OTHER

natural and commercial oral rinses were compared for efficacy

Interventions

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oral rinces

natural and commercial oral rinses were compared for efficacy

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

\*Participants with at least 10 sites of chronic mild gingivitis with bleeding on probing but not having periodontal pockets of greater than 3mm

Exclusion Criteria

* Participants/girls with any medical or dental disease,
* Participants/girls with any dental prosthesis,
* Those taken antibiotics in last 6 months,
* Those received any periodontal therapy in last 3 months
Minimum Eligible Age

20 Years

Maximum Eligible Age

25 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Multan Medical And Dental College

OTHER

Sponsor Role lead

Responsible Party

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Dr. Aeeza Malik

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Aeeza Malik, BDS, MDS

Role: PRINCIPAL_INVESTIGATOR

Multan Medical & Dental College

Locations

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Aeeza Malik

Multan Khurd, Punjab Province, Pakistan

Site Status

Countries

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Pakistan

Central Contacts

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Aeeza Malik, BDS, MDS

Role: CONTACT

+923089162634

Other Identifiers

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MMDC

Identifier Type: -

Identifier Source: org_study_id

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