Oral and Perioral Herpes Simplex Virus Infection Type I in a Five-month-old Infant: A Case Report

NCT ID: NCT04713423

Last Updated: 2021-01-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

1 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-10-19

Study Completion Date

2017-10-19

Brief Summary

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A five-month-old healthy girl who presented with painful herpetic gingivostomatitis and perioral vesicles.

Detailed Description

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The investigators present the case of a five-month-old healthy girl who presented with painful herpetic gingivostomatitis and perioral vesicles. The investigators discuss the pathophysiology of primary herpes simplex virus infection and the effect of maternal antibodies on the infant's immune system. In addition, the investigators explain the diagnosis, management, and prognosis of herpes simplex virus infection in young infants.

Conditions

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Herpes Simplex Virus Infection

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

OTHER

Interventions

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Diagnosis and treatment of the case

The infant was transferred to a hospital for better management of her infection. She was immediately started on intravenous acyclovir (20 mg/kg/6 h/5 d) while acetaminophen suppositories (80 mg/8 h/5 d) were given to lower her body temperature. In addition, other palliative drugs, such as diphenhydramine syrup (12.5 mg/5 mL, 2.5 mL orally) once-a-night for five days, were given to ease the effort of drinking and to aid in achieving good sleep. Upon completion of five days of therapy, the patient showed complete recovery and was subsequently discharged from the hospital free from symptoms.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Five-months-old infants or younger

Exclusion Criteria

* Six-months-old infants or older
Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Princess Nourah Bint Abdulrahman University

OTHER

Sponsor Role lead

Responsible Party

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Ashwag Yagoub Aloyouny

Senior registrar of Oral Medicine

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Ashwag Y Aloyouny

Role: PRINCIPAL_INVESTIGATOR

Princess Nourah Bint Abdulrahman University

Locations

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Princess Nourah Bint Abdulrahman University

Riyadh, , Saudi Arabia

Site Status

Countries

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Saudi Arabia

Other Identifiers

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PrincessNBAU

Identifier Type: -

Identifier Source: org_study_id

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