Use of a Connected Companion in Children With Cystic Fibrosis

NCT ID: NCT04705636

Last Updated: 2021-01-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-01-20

Study Completion Date

2021-06-30

Brief Summary

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The study will be conducted over a 6 months period. For the first three months, the child will be accompagned with a connected companion. After this period, the companion will be removed for three months in oder to prove this companion could improve treatment adherence for children suffering from cytolisis fibrosis.

This study will be conducted at the University Hospital Center of Rennes and Hospital Center of Saint-Brieuc.

Detailed Description

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In developed countries, chronic diseases with long-term therapy adherence is about 50%, according to the WHO report, and the adherence rate for regular intake of preventive therapies decreases to 28%.

For cystic fibrosis, rates are not much higher. Optimistic articles report an average compliance rate of 60%. Other articles report a rate of 50% which varies according to the age of the patient, the intake treatment complexity and burdensome drug treatment (physiotherapy achieves the lowest adherence with 38%), the disease understanding and the interest of treatment persuasion. Low adherence can also be the result of incorrect use of administration devices, for example for inhaled treatments. Technical errors are very frequent and affect around 30% of patients.

Families with children suffering from cystic fibrosis need daily support. Health professionals need to relay their recommendations at home. This is why new and funny tools dedicated to children with chronic illnesses are needed.

This trial will study the impact of connected companion named LEO® created by Ludocare company.

Study will be conducted as :

* V0 : Companion given to the child
* V1 : Companion removed after 3 months of use
* V2 : Follow-up done between 1 and 3 months after the period without companion

Conditions

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Cystic Fibrosis in Children Chronic Disease

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Connected device

Connected device for three months period to support children care

Group Type EXPERIMENTAL

Connected device named "Leo" from Ludocare society

Intervention Type DEVICE

Connected device named "Leo" from Ludocare society will be allocated to each child for three-months period. During this time, child will be helped to take all of his medication and specific care by this connected device.

Interventions

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Connected device named "Leo" from Ludocare society

Connected device named "Leo" from Ludocare society will be allocated to each child for three-months period. During this time, child will be helped to take all of his medication and specific care by this connected device.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Child volunteer from 3 to 11 years old
* Affected by cystic fibrosis
* With a prescription containing at least two medications twice a day
* Affiliation to the national health insurance
* Child and holder of the exercise of parental authority understands and speaks French
* The person exercising parental authority must have reached the age of majority.
* Collection of the written consent of one of the holders of the exercise of parental authority

Exclusion Criteria

* Non-voluntary child, under 3 years of age or over 12 years of age
* Family reluctant to technology
* Family without smartphone and/or wifi connection
* Failure to obtain the written consent of one of the holders of the exercise of parental authority
* Child involved in research involving the human person
Minimum Eligible Age

3 Years

Maximum Eligible Age

11 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Rennes University Hospital

OTHER

Sponsor Role collaborator

Centre Hospitalier de Saint-Brieuc

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Marie JAMIN

Role: PRINCIPAL_INVESTIGATOR

Centre Hospitalier de Saint-Brieuc

Locations

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Chu Rennes

Rennes, , France

Site Status NOT_YET_RECRUITING

Centre Hospitalier de Saint-Brieuc

Saint-Brieuc, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Marie JAMIN

Role: CONTACT

+33296017818

Gwenaëlle LE GARFF

Role: CONTACT

+33296017277

Facility Contacts

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Eric DENEUVILLE

Role: primary

Marie JAMIN

Role: primary

References

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De Geest S, Sabate E. Adherence to long-term therapies: evidence for action. Eur J Cardiovasc Nurs. 2003 Dec;2(4):323. doi: 10.1016/S1474-5151(03)00091-4. No abstract available.

Reference Type RESULT
PMID: 14667488 (View on PubMed)

Jentzsch NS, Camargos PAM, Colosimo EA, Bousquet J. Monitoring adherence to beclomethasone in asthmatic children and adolescents through four different methods. Allergy. 2009 Oct;64(10):1458-1462. doi: 10.1111/j.1398-9995.2009.02037.x. Epub 2009 Mar 28.

Reference Type RESULT
PMID: 19416142 (View on PubMed)

Zindani GN, Streetman DD, Streetman DS, Nasr SZ. Adherence to treatment in children and adolescent patients with cystic fibrosis. J Adolesc Health. 2006 Jan;38(1):13-7. doi: 10.1016/j.jadohealth.2004.09.013.

Reference Type RESULT
PMID: 16387243 (View on PubMed)

Conway SP, Pond MN, Hamnett T, Watson A. Compliance with treatment in adult patients with cystic fibrosis. Thorax. 1996 Jan;51(1):29-33. doi: 10.1136/thx.51.1.29.

Reference Type RESULT
PMID: 8658364 (View on PubMed)

Arias Llorente RP, Bousono Garcia C, Diaz Martin JJ. Treatment compliance in children and adults with cystic fibrosis. J Cyst Fibros. 2008 Sep;7(5):359-67. doi: 10.1016/j.jcf.2008.01.003. Epub 2008 Mar 4.

Reference Type RESULT
PMID: 18304896 (View on PubMed)

Sanchis J, Gich I, Pedersen S; Aerosol Drug Management Improvement Team (ADMIT). Systematic Review of Errors in Inhaler Use: Has Patient Technique Improved Over Time? Chest. 2016 Aug;150(2):394-406. doi: 10.1016/j.chest.2016.03.041. Epub 2016 Apr 7.

Reference Type RESULT
PMID: 27060726 (View on PubMed)

O'Donohoe R, Fullen BM. Adherence of subjects with cystic fibrosis to their home program: a systematic review. Respir Care. 2014 Nov;59(11):1731-46. doi: 10.4187/respcare.02990. Epub 2014 Jul 15.

Reference Type RESULT
PMID: 25233386 (View on PubMed)

Britto MT, Rohan JM, Dodds CM, Byczkowski TL. A Randomized Trial of User-Controlled Text Messaging to Improve Asthma Outcomes: A Pilot Study. Clin Pediatr (Phila). 2017 Dec;56(14):1336-1344. doi: 10.1177/0009922816684857. Epub 2017 Jan 5.

Reference Type RESULT
PMID: 28056541 (View on PubMed)

Related Links

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https://www.20minutes.fr/sante/2660383-20191129-maladies-comment-applications-objets-connectes-peuvent-aider-enfants-prendre-traitement

Maladies : Comment les applications et objets connectés peuvent aider les enfants à prendre leur traitement ?

Other Identifiers

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ID-RCB

Identifier Type: REGISTRY

Identifier Source: secondary_id

CHSB_202010_P3_COMPANION-CF

Identifier Type: -

Identifier Source: org_study_id

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