Investigation of Immune Modulation by Modern Acupuncture in Gastroenterologic Cancers
NCT ID: NCT04692454
Last Updated: 2020-12-31
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
5 participants
INTERVENTIONAL
2020-08-31
2020-11-30
Brief Summary
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Detailed Description
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The immune checkpoint or complementary therapy in the course of cancer treatment has been reported as effective methods for patients. In recent years, more integrated treatment studies have found that acupuncture can improve the discomfort and pain caused by chemotherapy. In addition, the treatment of rheumatoid arthritis has shown that acupuncture can effectively regulate the immunity of patients. In this study, investigators are considering to apply modern acupuncture as the immune modulation in gastroenterological cancers. Modern acupuncture is to use the scalp and ear acupuncture methods to identify diseases and checkpoints and apply them to regulate the immune function of patients with gastroenterological cancers. The infiltration of a specific subtype of T-cell and the expression of PD-L1 in tumors may be applied as indicators of cancer prognosis. These CD8 T cells (also called Tex cells) often fail to eradicate tumors and can become dysfunctional or exhausted. The magnitude of the reinvigoration of circulating Tex cells determined in relation to pretreatment tumor burden correlated with clinical response. By monitoring Tex cells, investigators will evaluate the feasibility of acupuncture as a complementary therapy to regulate the immune functions of patients with gastroenterological cancers
Conditions
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Keywords
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Study Design
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NA
SINGLE_GROUP
PREVENTION
NONE
Study Groups
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the scalp and ear acupuncture
CHIAN HUEI ACUPUNCTURE NEEDLE
Modern acupuncture
use the scalp and ear acupuncture methods to identify diseases and checkpoints and apply them to regulate the immune function of patients with gastroenterological cancers.
Interventions
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Modern acupuncture
use the scalp and ear acupuncture methods to identify diseases and checkpoints and apply them to regulate the immune function of patients with gastroenterological cancers.
Eligibility Criteria
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Inclusion Criteria
* Must have the will to receive acupuncture
Exclusion Criteria
* History of having bad reflect in acupuncture
* Coagulopathy
20 Years
75 Years
ALL
No
Sponsors
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Taipei Medical University WanFang Hospital
OTHER
Responsible Party
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Ming-Shun Wu
Director of GI
Principal Investigators
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Ming-Shun Wu, PHD
Role: STUDY_DIRECTOR
Taipei Municipal Wanfang Hospital
Locations
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WanFangH
Taipei, , Taiwan
Countries
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Other Identifiers
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N202005058
Identifier Type: -
Identifier Source: org_study_id