Swiss Postpartum Hypertension Cohort

NCT ID: NCT04690660

Last Updated: 2025-05-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Total Enrollment

480 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-06-04

Study Completion Date

2030-05-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This open label, prospective observational, single-center registry is to study short-, intermediate-and long-term course of postpartum hypertension and predictors/risk factors associated with long term cardiovascular and renal risk.

Current disease management strategies will be evaluated.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Postpartum Hypertension (PPHT)

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Data collection for parameters of organ damage (cardiac and renal blood markers)

Blood results will be taken out of next routine venipuncture. Routinely collected standard parameters are a blood count, chemistry panel including renal parameters and electrolytes, lipid profile and a HbA1c as well as albumin/creatinine and protein/creatinine ratio in urine.

Intervention Type OTHER

Data collection for blood pressure (BP)

Clinic blood pressure and 24hour BP Measurements

Intervention Type OTHER

Home-based blood pressure management (substudy)

Subjects participating in home-based blood pressure management via telemonitoring will receive a free HekaHealth application (App) for the structured assessment of HBPM.

Intervention Type OTHER

Biomarker Profiles (substudy)

Substudy where possible cardiac, renal and pregnancy related biomarkers will be additionally analyzed. The following biomarkers will be analyzed: N terminal (NT)-proBNP, Troponin, elevated mid-regional pro-atrial natriuretic peptide (ANP), elevated mid-regional pro adrenomedullin (ADM), soluble fms-like tyrosine kinase (sFlt-1), and placenta growth factor (PlGF).

Intervention Type OTHER

Data collection on patient reported outcomes

Data collection on patient reported outcomes (Questionnaire EQ-5D, Questionnaire for App based monitoring )

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* all women with hypertensive disorders of pregnancy
* postpartum hypertension (blood pressure measurements of systolic ≥140 and/or diastolic ≥ 90mmHg or antihypertensive therapy within the first 14 days after delivery)
* women with preexisting hypertension or
* women on antihypertensive medication

Exclusion Criteria

* delivery \> 14 days
* lack of consent to participate in the study, language barriers or lack of general understanding
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

University Hospital, Basel, Switzerland

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Thenral Socrates, Dr. med.

Role: PRINCIPAL_INVESTIGATOR

Medical Outpatient Department and Hypertension Clinic, University Hospital BaselUni

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Medical Outpatient Department and Hypertension Clinic, University Hospital Basel

Basel, , Switzerland

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

Switzerland

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Thenral Socrates, Dr. med.

Role: CONTACT

+41 61 328 6647

Thilo Burkard, Dr. med.

Role: CONTACT

+41 61 328 7738

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Thenral Socrates, Dr. med.

Role: primary

+41 61 328 6647

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

2020-00736; me20Burkard

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Intensive Postpartum Antihypertensive Treatment
NCT05687344 ACTIVE_NOT_RECRUITING PHASE3
Postpartum Readmission
NCT03026686 TERMINATED
Preeclampsia Postpartum Antihypertensive Treatment
NCT04298034 ACTIVE_NOT_RECRUITING PHASE3