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C-reactive Protein Levels in Acute Apical Abscess Due to Root Canal Infection

NCT ID: NCT04684407

Last Updated: 2020-12-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

200 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-11-01

Study Completion Date

2022-12-01

Brief Summary

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C-reactive protein levels of patients with acute apical abscess are evaluated before and after root canal treatment

Detailed Description

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In patients with acute apical abscess C-reactive proteins are evaluated before and after root canal treatment. In this intra-canal medications calcium hydroxide and triple antibiotic paste are compared. PAI score of the corresponding tooth is noted .

Conditions

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Dentoalveolar Abscess

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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calcium hydroxide

calcium hydroxide powder is mixed with normal saline and placed as intra-canal medication

Group Type ACTIVE_COMPARATOR

ROOT CANAL TREATMENT

Intervention Type PROCEDURE

TWO TYPE OF INTRA CANAL MEDICATION PLACEMENT

Triple antibiotic paste

Triple antibiotic paste (TAP)- combination of metronidazole,ciprofloxacin and minocycline mixed in a ratio of 1:1:1 .

TAP paste is combined with propylene glycol and placed as intra canal medication.

Group Type EXPERIMENTAL

ROOT CANAL TREATMENT

Intervention Type PROCEDURE

TWO TYPE OF INTRA CANAL MEDICATION PLACEMENT

Interventions

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ROOT CANAL TREATMENT

TWO TYPE OF INTRA CANAL MEDICATION PLACEMENT

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

patient with acute apical abscess

Exclusion Criteria

* Teeth with evidence of previous initiated root canal treatment
* History of myocardial infarction, coronary heart disease
* Patients allergic to local anesthetic
* Patients under steroid medication
* Patients who are immunocompromised
Minimum Eligible Age

16 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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CSI College of Dental Sciences and Research, Madurai

OTHER

Sponsor Role lead

Responsible Party

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Dr.Joyson Joe Asir.J

Post graduate student

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Csi College of Dental Sciences and Research

Madurai, Tamil Nadu, India

Site Status RECRUITING

Countries

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India

Facility Contacts

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JOYSON JOE ASIR J, MDS III YR

Role: primary

Other Identifiers

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CSIDentalCMadurai

Identifier Type: -

Identifier Source: org_study_id