Narrow Band Imaging (NBI) Under Electronic Bronchoscope in Lung Cancer

NCT ID: NCT04676815

Last Updated: 2023-05-23

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 200 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2023-06-30
• Study Completion Date: 2024-07-31

Brief Summary

Narrow-Band Imaging (NBI) is useful to better demarcate the superficial extent of central type of lung cancer, but its sensitivity and specificity in clinical practice were little studied. This study aimed to investigate the diagnostic effects of NBI in suspected patients with central lung cancer and its application in staging diagnosis of central lung cancer.

Detailed Description

With high morbidity and mortality, lung cancer is one of the most common tumors in the world. Therefore, early detection, accurate diagnosis and staging division can effectively guide clinical interventions, thereby improving patient survival. Narrowband imaging under electronic bronchoscope (NBI) is an emerging optical image emphasis technology that can enhance the contrast between the mucosal surface and underlying blood vessels, specifically display the distribution of blood vessels, and highlight the subtle changes in mucosal structure. Meanwhile, it can reduce unnecessary biopsy with low risk and costs. In recent years, NBI technology has gradually begun to show its unique advantages in the diagnosis of gastric cancer, esophageal cancer, nasopharyngeal cancer, and bladder cancer. The purpose of this study is to explore the diagnostic value of NBI under electronic bronchoscopy for early detection and accurate diagnosis of lung cancer, and to provide a more economical, safer and more efficient diagnosis option for lung cancer patients.

Conditions

Lung Cancer; Malignant Airway Obstruction

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

NBI PATIENT

Diagnostic Test: NBI in combination with electronic bronchoscope

NBI and interventional bronchoscopy

Intervention Type: PROCEDURE

NBI used to enhance the contrast between the mucosal surface and underlying blood vessels

Non-NBI PATIENT

Diagnostic Test: Electronic bronchoscope without NBI

No interventions assigned to this group

Interventions

NBI and interventional bronchoscopy

NBI used to enhance the contrast between the mucosal surface and underlying blood vessels

Intervention Type: PROCEDURE

Eligibility Criteria

Inclusion Criteria

• Patients had a history or current central lung cancer

Exclusion Criteria

• NONE

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 80 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Shanghai Pulmonary Hospital, Shanghai, China

OTHER

Sponsor Role: lead

Responsible Party

Yayi He

Associate Chief Physician

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Shanghai Pulmonary Hospital

Shanghai, , China

Countries

China

Central Contacts

Yayi He, Ph.D, MD

Role: CONTACT

2250601@qq.com

+8621 65115006

Facility Contacts

Yayi He, Ph.D

Role: primary

2250601@qq.com

+8621 65115006

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Other Identifiers

YHe

Identifier Type: -

Identifier Source: org_study_id