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Risk Benefit Ratio of Hirudotherapy: Retrospective Single-center Study of 37 Cases Over a Period of 9 Years

NCT ID: NCT04676581

Last Updated: 2020-12-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

37 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-12-15

Study Completion Date

2020-12-15

Brief Summary

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Venous congestion in transplanted or re-implanted tissues remains a common and chal-lenging complication in plastic and reconstructive surgery. Local application of medicinal leeches is effective to reduce postoperative venous congestion of the flap and to restore normal blood flow. However, leech therapy is associated with a number of risks, including infections. Indeed, leeches maintain a symbiotic relationship with Aeromonas species in order to digest blood in their gut. Aeromonas spp. infections can occur 1 to 30 days post-application of leeches and are associated with a dramatic decrease in flap salvage rates (88 to 30%). For these reasons, prophylactic antibiotics and, external decontamination are widely recommended throughout the course of leech therapy.

The aim of this study is to investigate the prevalence of side effects (anemia and infection) from patients treated with leeches in French Hospital.

Detailed Description

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Conditions

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Leeches Healthcare Associated Infection

Keywords

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Leeches Healthcare-associated infection Hirudo Medicinalis

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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Aeromonas infection

Leech Therapy

Intervention Type OTHER

Patient who received leeches (for more than 2 days) at the Amiens University Hospital over a period of 9 years (2010-2018)

No infected

Leech Therapy

Intervention Type OTHER

Patient who received leeches (for more than 2 days) at the Amiens University Hospital over a period of 9 years (2010-2018)

bacterial infection

Leech Therapy

Intervention Type OTHER

Patient who received leeches (for more than 2 days) at the Amiens University Hospital over a period of 9 years (2010-2018)

Interventions

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Leech Therapy

Patient who received leeches (for more than 2 days) at the Amiens University Hospital over a period of 9 years (2010-2018)

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patient who received leeches (for more than 2 days) at the Amiens University Hospital over a period of 9 years (2010-2018)

Exclusion Criteria

* Hirudotherapy outside the inclusion period
* Hirudotherapy or less than 2 days of treatment
Minimum Eligible Age

6 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Universitaire, Amiens

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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CHU Amiens

Amiens, , France

Site Status

Countries

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France

Other Identifiers

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PI2020_843_0136

Identifier Type: -

Identifier Source: org_study_id