A Multi-omics Study of Metastatic Prostate Cancer (MOSMPCA)

NCT ID: NCT04660617

Last Updated: 2021-05-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-08-01

Study Completion Date

2023-04-01

Brief Summary

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The investigators plan to perform multi-omics technologies, including genomic, transcriptomic, epigenomic and proteomic methods, in patients with metastatic prostate cancer, aiming at uncovering the mechanism of the tumor progression, identifying distinct tumor subtypes and finding new treatment targets.

Detailed Description

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Prostate cancer is the commonest malignancy and the second leading cause of tumor-related death among males worldwide. Though patients with early stage prostate cancer can obtain satisfactory therapeutic efficacy from radical prostatectomy or radiotherapy, the prognosis of men with metastatic prostate cancer (mPCa), especially metastatic castration-resistant prostate cancer (mCRPC), is still poor. Recent years have witnessed the rapid development of the high-throughput technologies, including genomic, transcriptomic, epigenomic and proteomic methods. These techniques are promising in uncovering the mechanism of the tumor progression, identifying distinct tumor subtypes and finding new treatment targets.

In the current prospective study, the investigators plan to perform multi-omics technologies in patients with mPCa, aiming at uncovering the mechanism of the tumor progression, identifying distinct tumor subtypes and finding new treatment targets.

Conditions

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Prostate Cancer Metastatic

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Pathological confirmation of prostate cancer
* Age: ≥40 years old
* Bone or visceral metastatic disease confirmed by image examination.
* Written informed consent

Exclusion Criteria

* Patients harbouring other types of cancer besides prostate cancer
Minimum Eligible Age

40 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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West China Hospital

OTHER

Sponsor Role lead

Responsible Party

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Hao Zeng

Vice director of the department of urology

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Hao Zeng, Dr.

Role: PRINCIPAL_INVESTIGATOR

West China Hospital

Central Contacts

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Jinge Zhao, Dr.

Role: CONTACT

86 13679017572

Other Identifiers

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MOSMPCA

Identifier Type: -

Identifier Source: org_study_id

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