A Pilot Study To Assess The Impact Of A Camstent Coated Catheter On Clinical Bacteriuria

NCT ID: NCT04658719

Last Updated: 2020-12-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-02-28

Study Completion Date

2021-12-31

Brief Summary

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A Pilot Study To Assess The Impact Of A Camstent Coated Catheter On Clinical Bacteriuria when compared to an uncoated catheter.

Each participant will take part in the trial from the time the participant signs the informed consent form (ICF).

After the screening visit, the participants will be allocated to either a coated catheter or an uncoated catheter. Participants will be assigned to receive trial treatment until the catheter has been removed, investigator's decision to withdraw the subject, noncompliance with trial treatment or procedures, unacceptable adverse event, or participant withdraws consent.

During the trial urine samples will be taken form the catheter port, temperature will be taken, and participants and healthcare providers will be asked to complete questionnaires.

Detailed Description

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Conditions

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Bacteriuria

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

DEVICE_FEASIBILITY

Blinding Strategy

NONE

Study Groups

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Camstent Coated Catheter

The patented 'M4D coating' is applied to inner and outer surfaces using a 'dip/dry' process before sterilisation, creating a safe, inert, and long-lasting finish. The coating reduces friction of the catheter surface, enhancing patient comfort on insertion and withdrawal. It also incorporates the materials which virtually preclude biofilm formation. The coating doesn't elute antibacterial agents or toxins, avoiding the build-up of dead bacteria on the device surface and retaining effectiveness throughout extended use (NB. Effectiveness is not lost because of leaching away of an active antimicrobial agent). Finally, the absence of anti-bacterial moieties means that the healthy microbial flora is not disturbed.

Group Type EXPERIMENTAL

Camstent Coated Catheter

Intervention Type DEVICE

The patented 'M4D coating' is applied to inner and outer surfaces using a 'dip/dry' process before sterilisation, creating a safe, inert, and long-lasting finish. The coating reduces friction of the catheter surface, enhancing patient comfort on insertion and withdrawal. It also incorporates the materials which virtually preclude biofilm formation. The coating doesn't elute antibacterial agents or toxins, avoiding the build-up of dead bacteria on the device surface and retaining effectiveness throughout extended use (NB. Effectiveness is not lost because of leaching away of an active antimicrobial agent). Finally, the absence of anti-bacterial moieties means that the healthy microbial flora is not disturbed.

Standard Care

Foley catheter, uncoated

Group Type ACTIVE_COMPARATOR

Standard Care

Intervention Type DEVICE

Uncoated Foley Catheter

Interventions

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Camstent Coated Catheter

The patented 'M4D coating' is applied to inner and outer surfaces using a 'dip/dry' process before sterilisation, creating a safe, inert, and long-lasting finish. The coating reduces friction of the catheter surface, enhancing patient comfort on insertion and withdrawal. It also incorporates the materials which virtually preclude biofilm formation. The coating doesn't elute antibacterial agents or toxins, avoiding the build-up of dead bacteria on the device surface and retaining effectiveness throughout extended use (NB. Effectiveness is not lost because of leaching away of an active antimicrobial agent). Finally, the absence of anti-bacterial moieties means that the healthy microbial flora is not disturbed.

Intervention Type DEVICE

Standard Care

Uncoated Foley Catheter

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Require insertion or exchange of a urinary catheter in a suprapubic position as a component of their routine clinical care as per guidelines
* Patients aged 18+ years will be eligible for the study.
* Patient understands and is willing to participate in the study and is able to comply with study procedures and visits.

Exclusion Criteria

* Patients that have or recently (within 3 weeks) had a urinary catheter and displays symptoms of current urinary tract infection.2. Patients that have asymptomatic infection (if required may need a blood test to confirm)
* Pregnant or Breastfeeding.
* Patients with a potentially immunocompromised conditions (HIV)
* Has a known silicone allergy or sensitivity
* Use of investigational drug or device within four weeks prior to study entry that may interfere with this study.
* Any medication deemed by the Investigator to potentially interfere with the study treatment
* Participation in any other clinical study.
* Has a known bloodstream infection or an infection that requires prolonged antibiotic therapy
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Camstent Ltd.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Central Contacts

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Prital Patel, MSc

Role: CONTACT

Phone: +44 (0)333 987 4050

Email: [email protected]

Related Links

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Other Identifiers

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CAM-SPC-001

Identifier Type: -

Identifier Source: org_study_id