Complementary and Integrative Pain Therapies and Functional Restoration (IMPPPORT) Trial)

NCT ID: NCT04656340

Last Updated: 2024-12-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

210 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-12-09

Study Completion Date

2019-04-02

Brief Summary

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This study aims to evaluate the benefit of a complementary and integrative health (CIH) pain management program when added to standard rehabilitative care (SC) compared to SC alone prior to an intensive functional restoration (FR) program in a population of active duty service members. In addition the study aims to identify factors that predict improvement in pain impact following treatment, and to determine the proportion of participants who experience clinically meaningful response.

SC included physical and occupational therapy. CIH included chiropractic, acupuncture, yoga and foam roller instruction. Both treatment groups also received education about pain psychology.

Participants were randomly assigned to a 3-week course of either SC alone or CIH combined with SC prior to a 3-week course of FR. Outcomes were collected at baseline, at end of stage 1, and post-FR. Outcomes included patient-reported and provider-determined measures.

Detailed Description

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Conditions

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Chronic Pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Randomized controlled trial
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Standard rehabilitative care (SC)

Twice weekly physical therapy, occupational therapy and pain psychoeducation

Group Type ACTIVE_COMPARATOR

non-medication, non-interventional therapies

Intervention Type OTHER

non-medication, non-interventional therapies

Complementary and Integrative Health (CIH) therapies in addition to Standard rehabilitate care (SC)

Twice weekly chiropractic, acupuncture, yoga and foam roller instruction, in addition to SC

Group Type EXPERIMENTAL

non-medication, non-interventional therapies

Intervention Type OTHER

non-medication, non-interventional therapies

Interventions

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non-medication, non-interventional therapies

non-medication, non-interventional therapies

Intervention Type OTHER

Other Intervention Names

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Standard rehabilitative therapies (SC) and Complementary and Integrative Health (CIH) therapies

Eligibility Criteria

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Inclusion Criteria

* Significant functional impairment due to pain, requiring modification of military duties.
* Physically able to participate in up to four hours of physical activity (strength, flexibility, endurance training) per day:

1. Can stand up from and sit down on floor independently
2. Can walk on treadmill for at least 6 minutes at 2.5 mile/hour pace or faster.
3. Able to complete at least 2 of the following:

1. Lift 20 lbs from floor to knuckle height
2. Lift 20 lbs from floor to shoulder height
3. Carry 20lbs at least 40 feet.
* Inadequate response to previous less intensive treatment
* Expresses motivation to take active role in regaining function

Exclusion Criteria

* Major surgeries within past 6 months or planned within next 6 months
* Unstable psychological disorders
* Active substance use disorder
* High dose opioids of \>120 milligrams of morphine equivalent doses (MED)/day
Minimum Eligible Age

18 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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U.S. Army Medical Research and Development Command

FED

Sponsor Role collaborator

University of Washington

OTHER

Sponsor Role collaborator

National Institute of Nursing Research (NINR)

NIH

Sponsor Role collaborator

Henry M. Jackson Foundation for the Advancement of Military Medicine

OTHER

Sponsor Role collaborator

Madigan Army Medical Center

FED

Sponsor Role lead

Responsible Party

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Diane Flynn

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

References

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Flynn DM, McQuinn H, Fairchok A, Eaton LH, Langford DJ, Snow T, Doorenbos AZ. Enhancing the success of functional restoration using complementary and integrative therapies: Protocol and challenges of a comparative effectiveness study in active duty service members with chronic pain. Contemp Clin Trials Commun. 2018 Nov 29;13:100311. doi: 10.1016/j.conctc.2018.100311. eCollection 2019 Mar.

Reference Type BACKGROUND
PMID: 30582069 (View on PubMed)

Flynn DM, McQuinn H, Burke L, Steffen A, Fairchok A, Snow T, Doorenbos AZ. Use of Complementary and Integrative Health Therapies Before Intensive Functional Restoration in Active Duty Service Members with Chronic Pain. Pain Med. 2022 Apr 8;23(4):844-856. doi: 10.1093/pm/pnab326.

Reference Type DERIVED
PMID: 34791423 (View on PubMed)

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Document Type: Informed Consent Form

View Document

Other Identifiers

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DM140424

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

K24NR015340

Identifier Type: NIH

Identifier Source: secondary_id

View Link

215050

Identifier Type: -

Identifier Source: org_study_id