A Clinical Trial to Evaluate the Preference Regarding Convenience of Medication and Efficacy/Safety of SUGAMET®XR Tablet 5/1000mg

NCT ID: NCT04653779

Last Updated: 2020-12-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE4

Total Enrollment

54 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-12-31

Study Completion Date

2021-07-31

Brief Summary

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Multi-center, open-label, single arm study to Evaluate the preference regarding convenience of medication, efficacy and safety of Sugamet XR tab. 5/1000mg in patients with Type 2 diabetes and renal diseases

Detailed Description

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Conditions

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Diabetes Mellitus, Type 2 Renal Disease Diabetes Mellitus Metabolic Disease Endocrine System Diseases

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Group A

Patients receive Evogliptin 5mg/Metformin 1000mg once a day

Group Type EXPERIMENTAL

Evogliptin 5mg/Metformin 1000mg

Intervention Type DRUG

Size reduction of a tablet formulation

Interventions

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Evogliptin 5mg/Metformin 1000mg

Size reduction of a tablet formulation

Intervention Type DRUG

Other Intervention Names

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SUGAMET®XR tablet 5/1000mg

Eligibility Criteria

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Inclusion Criteria

* Aged ≥60 years
* Subjects with type 2 diabetes mellitus
* Subjects treated with DPP-4 inhibitor and 1,000mg/day dose of metformin 1T/qd for at least 8 weeks prior to screening
* Subjects with HbA1c≤7.5% at screening
* Subjects with 45mL/min/1.73m2≤eGFR≤90mL/min/1.73m2 at screening
* Subjects with fasting glucose≤200 at screening
* Subjects with 18.5kg/m2≤BMI≤40kg/m2 at screening

Exclusion Criteria

* Patients with type 1 diabetes mellitus, secondary diabetes mellitus or gestational diabetes mellitus
* ESRD or Patients who have kidney dialysis
* Subjects with ALT and AST 3 times or higher than upper normal range
Minimum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Dong-A ST Co., Ltd.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Suncheonhyang Bucheon Hospital

Bucheon-si, Gyeonggi-do, South Korea

Site Status

Se-jong hospital

Bucheon-si, Gyeonggi-do, South Korea

Site Status

Countries

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South Korea

Central Contacts

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Sung

Role: CONTACT

Phone: 82-2-920-8369

Email: [email protected]

Facility Contacts

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Suncheonhyang Bucheon Hospital

Role: primary

Se-jong hospital

Role: primary

Other Identifiers

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DA1229_01_DM_IV

Identifier Type: -

Identifier Source: org_study_id