Shanghai Meiji Health Science and Technology Co., Ltd

NCT ID: NCT04651023

Last Updated: 2020-12-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

95 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-01-10

Study Completion Date

2009-06-20

Brief Summary

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Investigators performed a randomized double-blind trial to determine the effects of long-term NnEx ingestion in patients with overweight or obesity. Ninety-five participants (23\<BMI\<30 kg/m2) were randomly allocated to three groups: a control group, a 1 g/day NnEx group, and a 2 g/day NnEx group. The effects of the consumption of 2 g/day or 1 g/day NnEx for 12 weeks on indices of adiposity and fasting blood metabolic parameters were compared with those of no consumption of NnEx.

Detailed Description

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Conditions

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Over Weight People

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

DOUBLE

Participants Caregivers

Study Groups

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control group

During the 12-week study period, the participants consumed two bottles (2 \*200 mL) of the experimental beverage (0g NnEx) per day with or after meals.

Group Type PLACEBO_COMPARATOR

Nelumbo nucifera Leaf Extract

Intervention Type DIETARY_SUPPLEMENT

Hot water extracted Nelumbo nucifera Leaf, mainly containing quercetin and quercetin 3-O-glucuronide.

low concentration of NnEx group

During the 12-week study period, the participants consumed two bottles (2 \*200 mL) of the experimental beverage (1g NnEx) per day with or after meals.

Group Type EXPERIMENTAL

Nelumbo nucifera Leaf Extract

Intervention Type DIETARY_SUPPLEMENT

Hot water extracted Nelumbo nucifera Leaf, mainly containing quercetin and quercetin 3-O-glucuronide.

high concentration of NnEx group

During the 12-week study period, the participants consumed two bottles (2 \*200 mL) of the experimental beverage (2g NnEx) per day with or after meals.

Group Type EXPERIMENTAL

Nelumbo nucifera Leaf Extract

Intervention Type DIETARY_SUPPLEMENT

Hot water extracted Nelumbo nucifera Leaf, mainly containing quercetin and quercetin 3-O-glucuronide.

Interventions

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Nelumbo nucifera Leaf Extract

Hot water extracted Nelumbo nucifera Leaf, mainly containing quercetin and quercetin 3-O-glucuronide.

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Has a body mass index (BMI) of 23-30 kg/m2
* Has no history of using any antidiabetic medication
* Absence of liver, kidney, or heart disease
* Absence of food allergy and daily tea consumption \<2 L
* Meet all of the above criteria and to follow the instructions given during the study.

Exclusion Criteria

* Testing delayed for \>1 week without justification
* Difficulty attending the hospital on the required days
* Lack of data regarding the times of beverage consumption for over 5% of the study
* Abnormal overeating
* Test results believed to be unreliable because of the lack of provision of diet and exercise reports during the fasting period
* Difficulty drawing blood
* Poor confidence in the test data
Minimum Eligible Age

40 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Shanghai Meiji Health Science and Technology Co., Ltd.

INDUSTRY

Sponsor Role lead

Responsible Party

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Zai-Si Ji, phD

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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ShanghaiMHST

Identifier Type: -

Identifier Source: org_study_id