Trial Outcomes & Findings for Lifestyle Behavior Weight Loss Intervention (NCT NCT04649047)

NCT ID: NCT04649047

Last Updated: 2025-01-31

Results Overview

Self-reported body weight

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

15 participants

Primary outcome timeframe

baseline (T1) and 3 weeks follow up (T2)

Results posted on

2025-01-31

Participant Flow

Participant milestones

Participant milestones
Measure
Intervention
All participants will be assigned to the experimental group and receive a 3-weekly intervention via web and individual health coaching. The educational topics cover stress management, healthy eating, and physical activity Goal-oriented episodic future thinking: All participants will receive a 3-week web-based intervention plus individual health coaching. The intervention topics include stress management, healthy eating, and physical activity
Overall Study
STARTED
15
Overall Study
COMPLETED
12
Overall Study
NOT COMPLETED
3

Reasons for withdrawal

Reasons for withdrawal
Measure
Intervention
All participants will be assigned to the experimental group and receive a 3-weekly intervention via web and individual health coaching. The educational topics cover stress management, healthy eating, and physical activity Goal-oriented episodic future thinking: All participants will receive a 3-week web-based intervention plus individual health coaching. The intervention topics include stress management, healthy eating, and physical activity
Overall Study
Withdrawal by Subject
3

Baseline Characteristics

Lifestyle Behavior Weight Loss Intervention

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Intervention
n=15 Participants
All participants will be assigned to the experimental group and receive a 3-weekly intervention via web and individual health coaching. The educational topics cover stress management, healthy eating, and physical activity Goal-oriented episodic future thinking: All participants will receive a 3-week web-based intervention plus individual health coaching. The intervention topics include stress management, healthy eating, and physical activity
Age, Continuous
32.9 years
STANDARD_DEVIATION 6.9 • n=5 Participants
Sex: Female, Male
Female
15 Participants
n=5 Participants
Sex: Female, Male
Male
0 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
2 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
13 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants
n=5 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=5 Participants
Race (NIH/OMB)
Asian
0 Participants
n=5 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=5 Participants
Race (NIH/OMB)
Black or African American
7 Participants
n=5 Participants
Race (NIH/OMB)
White
7 Participants
n=5 Participants
Race (NIH/OMB)
More than one race
1 Participants
n=5 Participants
Race (NIH/OMB)
Unknown or Not Reported
0 Participants
n=5 Participants
Region of Enrollment
United States
15 Participants
n=5 Participants
Marital Status
Single (never married)
8 Participants
n=5 Participants
Marital Status
Married
5 Participants
n=5 Participants
Marital Status
Divorced
2 Participants
n=5 Participants
Education
High School/GED
1 Participants
n=5 Participants
Education
Some College/Technical School (no degree)
5 Participants
n=5 Participants
Education
Associate's Degree
1 Participants
n=5 Participants
Education
Bachelor's Degree
4 Participants
n=5 Participants
Education
Master's Degrees.
4 Participants
n=5 Participants
Employment
Full-Time
4 Participants
n=5 Participants
Employment
Part-Time
3 Participants
n=5 Participants
Employment
Self-Employed
1 Participants
n=5 Participants
Employment
Not employed outside of home
7 Participants
n=5 Participants

PRIMARY outcome

Timeframe: baseline (T1) and 3 weeks follow up (T2)

Self-reported body weight

Outcome measures

Outcome measures
Measure
Intervention
n=12 Participants
All participants will be assigned to the experimental group and receive a 3-weekly intervention via web and individual health coaching. The educational topics cover stress management, healthy eating, and physical activity Goal-oriented episodic future thinking: All participants will receive a 3-week web-based intervention plus individual health coaching. The intervention topics include stress management, healthy eating, and physical activity
Change in Body Weight
T1 (baseline)
194.1 pounds
Standard Deviation 38.04
Change in Body Weight
T2 (post-intervention)
191.2 pounds
Standard Deviation 37.70
Change in Body Weight
T2 vs. T2
-2.92 pounds
Standard Deviation 4.23

SECONDARY outcome

Timeframe: baseline (T1) and 3 weeks follow up (T2)

kg/m\^2

Outcome measures

Outcome measures
Measure
Intervention
n=12 Participants
All participants will be assigned to the experimental group and receive a 3-weekly intervention via web and individual health coaching. The educational topics cover stress management, healthy eating, and physical activity Goal-oriented episodic future thinking: All participants will receive a 3-week web-based intervention plus individual health coaching. The intervention topics include stress management, healthy eating, and physical activity
Body Mass Index
T1 (baseline)
32.14 kg/m2
Standard Deviation 5.23
Body Mass Index
T2 (post-intervention)
31.58 kg/m2
Standard Deviation 5.20
Body Mass Index
Change from T1 to T2
-.56 kg/m2
Standard Deviation .73

SECONDARY outcome

Timeframe: baseline (T1) and 3 weeks follow up (T2)

NCI brief dietary fat intake survey was used to measure dietary fat intake. Participants reported the frequency of each specific food eaten over the past 12 months. Values are:1 = never, 2 = less than once per month,3 = 1-3 times per week, 4 = 3-4 times per week,5 = 5-6 times per week, 6 = 1 time per day, 7 = 2 or more times per day. Higher scores indicate more frequent fat intake.There is no minimum or maximum available for this measure. The following procedures were used to convert an individual's responses to an estimate of that individual's percentage energy from fat: The frequency reported categorically on the questionnaire was converted to the number of times fat was consumed per day as shown below. In general, the midpoint of the frequency range was used. Never 0.0 Less than once a month 0.018 1-3 times per month 0.066 1-2 times per week 0.214 3-4 times per week 0.499 5-6 times per week 0.784 1. time per day 1.0 2. or more times per day 2.0

Outcome measures

Outcome measures
Measure
Intervention
n=12 Participants
All participants will be assigned to the experimental group and receive a 3-weekly intervention via web and individual health coaching. The educational topics cover stress management, healthy eating, and physical activity Goal-oriented episodic future thinking: All participants will receive a 3-week web-based intervention plus individual health coaching. The intervention topics include stress management, healthy eating, and physical activity
Daily Dietary Fat Intake
T2 (post-intervention)
31.17 Times fat consumed per day
Standard Deviation 5.06
Daily Dietary Fat Intake
T2 vs. T1
-3.42 Times fat consumed per day
Standard Deviation 6.72
Daily Dietary Fat Intake
T1 (baseline)
34.59 Times fat consumed per day
Standard Deviation 4.93

SECONDARY outcome

Timeframe: baseline (T1) and 3 weeks follow up (T2)

NCI brief Fruit and Vegetable intake survey was used to measure dietary intake. Participants reported the frequency of each specific food eaten over the past 12 months. Values are:1 = never, 2 = less than once per month,3 = 1-3 times per week, 4 = 3-4 times per week,5 = 5-6 times per week, 6 = 1 time per day, 7 = 2 or more times per day. Higher scores indicate more frequent fruit and vegetable intake.There is no minimum or maximum available for this measure. The frequency reported categorically on the questionnaire was converted to the number of times fruits/vegetables were consumed per day as shown below. In general, the midpoint of the frequency range was used. Frequency ResponseTimes Per Day Never 0.0 Less than once a month 0.018 1-3 times per month 0.066 1-2 times per week 0.214 3-4 times per week 0.499 5-6 times per week 0.784 1. time per day 1.0 2. or more times per day 2.0

Outcome measures

Outcome measures
Measure
Intervention
n=12 Participants
All participants will be assigned to the experimental group and receive a 3-weekly intervention via web and individual health coaching. The educational topics cover stress management, healthy eating, and physical activity Goal-oriented episodic future thinking: All participants will receive a 3-week web-based intervention plus individual health coaching. The intervention topics include stress management, healthy eating, and physical activity
Daily Fruit and Vegetable Intake
T2 (post-intervention)
5.72 Times fruit/vegetable consumed per day
Standard Deviation 3.43
Daily Fruit and Vegetable Intake
T2 vs. T1
0.85 Times fruit/vegetable consumed per day
Standard Deviation 1.75
Daily Fruit and Vegetable Intake
T1 (baseline)
4.87 Times fruit/vegetable consumed per day
Standard Deviation 3.42

SECONDARY outcome

Timeframe: baseline (T1) and 3 weeks follow up (T2)

NCI brief Added Sugar intake survey was used to measure dietary intake. Participants reported the frequency of each specific food eaten over the past 12 months. Values are:1 = never, 2 = less than once per month,3 = 1-3 times per week, 4 = 3-4 times per week,5 = 5-6 times per week, 6 = 1 time per day, 7 = 2 or more times per day. Higher scores indicate more frequent fat intake.There is no minimum or maximum available for this measure. The frequency reported categorically on the questionnaire was converted to the number of times consumed per day as shown below. In general, the midpoint of the frequency range was used. Frequency ResponseTimes Per Day Never 0.0 Less than once a month 0.018 1-3 times per month 0.066 1-2 times per week 0.214 3-4 times per week 0.499 5-6 times per week 0.784 1. time per day 1.0 2. or more times per day 2.0

Outcome measures

Outcome measures
Measure
Intervention
n=12 Participants
All participants will be assigned to the experimental group and receive a 3-weekly intervention via web and individual health coaching. The educational topics cover stress management, healthy eating, and physical activity Goal-oriented episodic future thinking: All participants will receive a 3-week web-based intervention plus individual health coaching. The intervention topics include stress management, healthy eating, and physical activity
Frequency of Added Sugar Intake
T2 (post-intervention)
12.53 Times added sugar consumed per day
Standard Deviation 8.32
Frequency of Added Sugar Intake
T2 vs. T1
-8.54 Times added sugar consumed per day
Standard Deviation 17.88
Frequency of Added Sugar Intake
T1 (baseline)
21.07 Times added sugar consumed per day
Standard Deviation 14.88

SECONDARY outcome

Timeframe: baseline (T1) and 3 weeks follow up (T2)

The International Physical Activity Questionnaire Short Form (7 items) was be used to measure physical activity. Participants are asked to report frequency (days/week) and duration (hours/ day or minutes/day) of vigorous and moderate physical activities performed in the past 7 days. Participants were asked about 3 specific types of activity: walking, moderate-intensity activity, and vigorous-intensity activity. Participants also reported frequency (days per week) and duration (time per day) for each specific type of activity. To create metabolic equivalent of task (MET, energy expenditure) measures, we multiplied frequency by duration (in hours). We then used the summation times 3.3 MET (walking), 4.0 (moderate physical activity), and 8.0 (vigorous physical activity) to generate physical activity scores in MET units. Higher scores indicated more energy expenditure.

Outcome measures

Outcome measures
Measure
Intervention
n=12 Participants
All participants will be assigned to the experimental group and receive a 3-weekly intervention via web and individual health coaching. The educational topics cover stress management, healthy eating, and physical activity Goal-oriented episodic future thinking: All participants will receive a 3-week web-based intervention plus individual health coaching. The intervention topics include stress management, healthy eating, and physical activity
Daily Physical Activity (Metabolic Equivalent Task MET)
T1 (baseline)
107.0 MET - Minutes per week
Standard Deviation 249.6
Daily Physical Activity (Metabolic Equivalent Task MET)
T2 (post-interveion)
171.5 MET - Minutes per week
Standard Deviation 390.0
Daily Physical Activity (Metabolic Equivalent Task MET)
T2 vs. T1
64.46 MET - Minutes per week
Standard Deviation 504.1

SECONDARY outcome

Timeframe: baseline (T1) and 3 weeks follow up (T2)

Autonomous motivation. To measure autonomous motivation, we used the Treatment Self-Regulation Questionnaire (6 items for stress management). Participants rated how true each statement was for them related to stress management using a 7-point scale: 1 (not at all true) to 7 (very true). We summed responses to the 6 items to create a score for stress management. Scores can range from 6 - 42. Higher scores indicated higher autonomous motivation.

Outcome measures

Outcome measures
Measure
Intervention
n=12 Participants
All participants will be assigned to the experimental group and receive a 3-weekly intervention via web and individual health coaching. The educational topics cover stress management, healthy eating, and physical activity Goal-oriented episodic future thinking: All participants will receive a 3-week web-based intervention plus individual health coaching. The intervention topics include stress management, healthy eating, and physical activity
Change in Autonomous Motivation for Stress Management
T2 (post-intervention)
40.00 score on a scale
Standard Deviation 2.83
Change in Autonomous Motivation for Stress Management
T2 vs. T1
3.50 score on a scale
Standard Deviation 3.97
Change in Autonomous Motivation for Stress Management
T1 (baseline)
36.50 score on a scale
Standard Deviation 4.87

SECONDARY outcome

Timeframe: baseline (T1) and 3 weeks follow up (T2)

Autonomous motivation. To measure autonomous motivation, we used the Treatment Self-Regulation Questionnaire (6 items for healthy eating). Participants rated how true each statement was for them related to healthier eating using a 7-point scale: 1 (not at all true) to 7 (very true). We summed responses to the 6 items to create a score for healthy eating. Scores can range from 6 - 42 Higher scores indicated higher autonomous motivation.

Outcome measures

Outcome measures
Measure
Intervention
n=12 Participants
All participants will be assigned to the experimental group and receive a 3-weekly intervention via web and individual health coaching. The educational topics cover stress management, healthy eating, and physical activity Goal-oriented episodic future thinking: All participants will receive a 3-week web-based intervention plus individual health coaching. The intervention topics include stress management, healthy eating, and physical activity
Change in Autonomous Motivation for Healthy Eating
T2 vs. T1
2.67 score on a scale
Standard Deviation 3.58
Change in Autonomous Motivation for Healthy Eating
T1 (baseline)
37.58 score on a scale
Standard Deviation 4.01
Change in Autonomous Motivation for Healthy Eating
T2 (post-intervention)
40.25 score on a scale
Standard Deviation 3.22

SECONDARY outcome

Timeframe: baseline (T1) and 3 weeks follow up (T2)

Autonomous motivation. To measure autonomous motivation, we used the Treatment Self-Regulation Questionnaire (6 items for physical activity). Participants rated how true each statement was for them related to physical activity using a 7-point scale: 1 (not at all true) to 7 (very true). We summed responses to the 6 items to create a score for physical activity. Scores can range from 6 -42. Higher scores indicated higher autonomous motivation.

Outcome measures

Outcome measures
Measure
Intervention
n=12 Participants
All participants will be assigned to the experimental group and receive a 3-weekly intervention via web and individual health coaching. The educational topics cover stress management, healthy eating, and physical activity Goal-oriented episodic future thinking: All participants will receive a 3-week web-based intervention plus individual health coaching. The intervention topics include stress management, healthy eating, and physical activity
Change in Autonomous Motivation for Physical Activity
T1 (baseline)
36.00 score on a scale
Standard Deviation 5.72
Change in Autonomous Motivation for Physical Activity
T2 (post-intervention)
40.50 score on a scale
Standard Deviation 2.71
Change in Autonomous Motivation for Physical Activity
T2 vs. T1
4.50 score on a scale
Standard Deviation 5.79

SECONDARY outcome

Timeframe: baseline (T1) and 3 weeks follow up (T2)

Self-efficacy. We used surveys to measure self-efficacy. We also used the general self-efficacy scale (10 items) to measure self-efficacy. Participants rated the truthfulness of each statement using a 4-point scale: 1 (not at all true) to 4 (exactly true). We summed responses to the 10 items to create a score for general self-efficacy. Scores can range from 10 - 40. Higher scores meant higher self-efficacy.

Outcome measures

Outcome measures
Measure
Intervention
n=12 Participants
All participants will be assigned to the experimental group and receive a 3-weekly intervention via web and individual health coaching. The educational topics cover stress management, healthy eating, and physical activity Goal-oriented episodic future thinking: All participants will receive a 3-week web-based intervention plus individual health coaching. The intervention topics include stress management, healthy eating, and physical activity
Change in General Self-efficacy
T1 (baseline)
31.42 score on a scale
Standard Deviation 5.18
Change in General Self-efficacy
T2 (post-intervention)
34.83 score on a scale
Standard Deviation 4.24
Change in General Self-efficacy
T2 vs. T1
3.42 score on a scale
Standard Deviation 5.88

SECONDARY outcome

Timeframe: baseline (T1) and 3 weeks follow up (T2)

Self-efficacy. We used surveys to measure self-efficacy for healthy eating (8 items). Participants rated levels of confidence using a 4-point scale: 1 (not at all confident) to 4 (very confident). We summed responses to the 8 items to create a score for self-efficacy for healthy eating. THigher scores meant higher self-efficacy. Participants rated the truthfulness of each statement using a 4-point scale: 1 (not at all true) to 4 (exactly true). We summed responses to the 10 items to create a score for general self-efficacy. Scores can range from 8 - 32. Higher scores meant higher self-efficacy.

Outcome measures

Outcome measures
Measure
Intervention
n=12 Participants
All participants will be assigned to the experimental group and receive a 3-weekly intervention via web and individual health coaching. The educational topics cover stress management, healthy eating, and physical activity Goal-oriented episodic future thinking: All participants will receive a 3-week web-based intervention plus individual health coaching. The intervention topics include stress management, healthy eating, and physical activity
Change in Healthy Eating Self-efficacy
T1 (baseline)
19.83 score on a scale
Standard Deviation 4.90
Change in Healthy Eating Self-efficacy
T2 (post-intervention)
22.25 score on a scale
Standard Deviation 4.88
Change in Healthy Eating Self-efficacy
T2 vs. T1
2.42 score on a scale
Standard Deviation 3.96

SECONDARY outcome

Timeframe: baseline (T1) and 3 weeks follow up (T2)

Self-efficacy. We used surveys to measure physical activity (10 items). Participants rated levels of confidence using a 4-point scale: 1 (not at all confident) to 4 (very confident). We summed responses to the 10 items to create a score for self-efficacy for physical activity. Higher scores meant higher self-efficacy. Participants rated the truthfulness of each statement using a 4-point scale: 1 (not at all true) to 4 (exactly true). We summed responses to the 10 items to create a score for general self-efficacy. Scores can range from 10 - 40. Higher scores meant higher self-efficacy.

Outcome measures

Outcome measures
Measure
Intervention
n=12 Participants
All participants will be assigned to the experimental group and receive a 3-weekly intervention via web and individual health coaching. The educational topics cover stress management, healthy eating, and physical activity Goal-oriented episodic future thinking: All participants will receive a 3-week web-based intervention plus individual health coaching. The intervention topics include stress management, healthy eating, and physical activity
Change in Physical Activity Self-efficacy
T2 vs. T1
3.83 score on a scale
Standard Deviation 8.39
Change in Physical Activity Self-efficacy
T1 (baseline)
25.33 score on a scale
Standard Deviation 7.18
Change in Physical Activity Self-efficacy
T2 (post-intervention)
29.17 score on a scale
Standard Deviation 7.41

SECONDARY outcome

Timeframe: baseline (T1) and 3 weeks follow up (T2)

Emotional control. To measure emotional control, we used the Emotion Regulation Questionnaire to assess the emotional regulatory process using reappraisal (6 items) and suppression (4 items). Participants rated the degree of agreement using a 7-point scale: 1 (strongly disagree) to 7 (strongly agree). The suppression items were reverse coded prior to score computation. We summed responses to the 10 items to create a score for emotional control. Scores could range between 10 - 70. Higher scores meant better emotional control.

Outcome measures

Outcome measures
Measure
Intervention
n=12 Participants
All participants will be assigned to the experimental group and receive a 3-weekly intervention via web and individual health coaching. The educational topics cover stress management, healthy eating, and physical activity Goal-oriented episodic future thinking: All participants will receive a 3-week web-based intervention plus individual health coaching. The intervention topics include stress management, healthy eating, and physical activity
Change in Emotion Regulation
T1 (baseline)
38.50 units on a scale
Standard Deviation 8.34
Change in Emotion Regulation
T2 (post-intervention)
42.58 units on a scale
Standard Deviation 10.61
Change in Emotion Regulation
T2 vs. T1
4.08 units on a scale
Standard Deviation 5.74

SECONDARY outcome

Timeframe: baseline (T1) and 3 weeks follow up (T2)

We used the Perceived Stress Scale (10 items) to measure stress. Participants rated the frequency of stressful life situations in the past month using a 4-point scale: 1 (never) to 4 (often). We summed responses to the 10 items to create a score for stress. Scores can range from 10-40. Higher scores meant perceived higher levels of stress.

Outcome measures

Outcome measures
Measure
Intervention
n=12 Participants
All participants will be assigned to the experimental group and receive a 3-weekly intervention via web and individual health coaching. The educational topics cover stress management, healthy eating, and physical activity Goal-oriented episodic future thinking: All participants will receive a 3-week web-based intervention plus individual health coaching. The intervention topics include stress management, healthy eating, and physical activity
Change in Perceived Stress
T1 (baseline)
18.33 score on a scale
Standard Deviation 6.10
Change in Perceived Stress
T2 (post-inbtervention)
14.67 score on a scale
Standard Deviation 6.64
Change in Perceived Stress
T2 vs. T1
-3.67 score on a scale
Standard Deviation 7.01

Adverse Events

Intervention

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr. Mei-Wei Chang

Ohio State University College of Nursing

Phone: 614-247-7211

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place