The Effect of Fertility Health Awareness Strategies on Fertility Knowledge and Childbearing in Young Married Couples

NCT ID: NCT04647136

Last Updated: 2025-04-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

841 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-01-21

Study Completion Date

2024-03-15

Brief Summary

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Singapore, like many developed countries, is experiencing low birth rates, which is coupled with increasing age at first marriage and birth. In addition, demand for assisted reproduction technology treatments has increased over the years. Fertility awareness surveys have consistently shown that public awareness of age-related fertility decline and the limitations of fertility treatments is generally low, and this may lead to couples not optimising their fertility potential to achieve their family aspirations. This trial aims to study the effect of fertility health screening and fertility awareness tools on knowledge, attitudes and practice around childbearing among young Singaporean married couples.

Detailed Description

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Conditions

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Fertility Awareness Childbearing Intentions

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Fertility Health Screening

Clinic-based fertility health screening and counselling

Group Type ACTIVE_COMPARATOR

Fertility Health Screening

Intervention Type DIAGNOSTIC_TEST

Basic fertility health screening comprising an anti-Mullerian hormone (AMH) test and semen analysis, a doctor's consultation to explain the results, and standardised reproductive counselling by a trained nurse comprising a discussion of reproductive plans (including addressing barriers the couple face), education on age-related fertility decline and limitations of artificial reproductive technologies, advice on the optimal reproductive timing and when to seek further help. An educational brochure will be handed to the couple during the counselling session.

Fertility Awareness Tools

Online intervention to provide fertility education and behavioural nudge for optimal reproductive timing.

Group Type ACTIVE_COMPARATOR

Fertility Awareness Tools

Intervention Type BEHAVIORAL

Online intervention consisting of 1) video targeting fertility education and specific attitudes, social norms and perceived control for having children, 2) a fertility awareness tool (FERTISTAT) and 3) an educational brochure on fertility. This intervention can be self-administered and is therefore easily scalable.

Control

No intervention

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Fertility Health Screening

Basic fertility health screening comprising an anti-Mullerian hormone (AMH) test and semen analysis, a doctor's consultation to explain the results, and standardised reproductive counselling by a trained nurse comprising a discussion of reproductive plans (including addressing barriers the couple face), education on age-related fertility decline and limitations of artificial reproductive technologies, advice on the optimal reproductive timing and when to seek further help. An educational brochure will be handed to the couple during the counselling session.

Intervention Type DIAGNOSTIC_TEST

Fertility Awareness Tools

Online intervention consisting of 1) video targeting fertility education and specific attitudes, social norms and perceived control for having children, 2) a fertility awareness tool (FERTISTAT) and 3) an educational brochure on fertility. This intervention can be self-administered and is therefore easily scalable.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Married couple
* Both partners should be Singapore Citizens or Permanent Residents
* Female partner is 25 - 34 years old at time of recruitment
* Both partners agreeable and able to complete study procedures

Exclusion Criteria

* Already have children, including from previous marriages
* Pregnant
* Currently undergoing or had previously went for any fertility evaluation and/or treatments
* Self-reported history of previous ectopic pregnancy in the female partner
* At least 1 partner unable to complete a self-administered questionnaire in English
Minimum Eligible Age

25 Years

Maximum Eligible Age

34 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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KK Women's and Children's Hospital

OTHER_GOV

Sponsor Role collaborator

Singapore Health Services

OTHER

Sponsor Role collaborator

Duke-NUS Graduate Medical School

OTHER

Sponsor Role collaborator

Cardiff University

OTHER

Sponsor Role collaborator

National Population and Talent Division

UNKNOWN

Sponsor Role collaborator

Singapore General Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Singapore General Hospital

Singapore, , Singapore

Site Status

KK Women's and Children's Hospital

Singapore, , Singapore

Site Status

Countries

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Singapore

References

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Chan SL, Thumboo J, Boivin J, Saffari SE, Yin S, Yeo SR, Chan JKY, Ng KC, Chua KH, Yu SL. Effect of fertility health awareness strategies on fertility knowledge and childbearing in young married couples (FertStart): study protocol for an effectiveness-implementation hybrid type I multicentre three-arm parallel group open-label randomised clinical trial. BMJ Open. 2022 Jan 3;12(1):e051710. doi: 10.1136/bmjopen-2021-051710.

Reference Type DERIVED
PMID: 34980614 (View on PubMed)

Other Identifiers

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7.0

Identifier Type: -

Identifier Source: org_study_id

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