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Volume Assessment of the Periapical Healing Following Regenerative Endodontic Procedures Using Cone- Bean Computed Tomography

NCT ID: NCT04646538

Last Updated: 2020-11-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

EARLY_PHASE1

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-06-05

Study Completion Date

2018-12-30

Brief Summary

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3D volume assessment was done to evaluate the periapical healing following REPs in mature teeth.

Detailed Description

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REPs were done for 10 mature maxillary necrotic teeth with periapical lesions confirmed by digital periapical radiographs. Instrumentation was done using Protaper Next till size X3 (size 30). Pre-operative radiographs also included CBCT scans to measure the 3D volume and area of the periapical lesion to be used as baseline data. The postoperative radiographic examination included: a) digital periapical radiographs taken at 3,6,9, and 12 months to monitor the lesion through out the follow-up period. b)CBCT scan to measure quantitatively the volume and area of the periapical lesion after 12 months follow up

Conditions

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Necrotic Pulp Periapical; Infection

Keywords

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REPs CBCT volume Mature teeth

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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X3 group

Group Type EXPERIMENTAL

Regenerative Endodontics Procedures (REPs)

Intervention Type OTHER

REPs was done for 10 mature maxillary necrotic teeth with periapical lesions. Instrumentation was done using Protaper Next system till size X3. Irrigation with 1.5 % NaOCl was done in the first visit. in the second visit, bleeding was induced in the canal by irritating the periapical area followed by the application of Biodentine as cervical plug then completion of the coronal restoration.

Interventions

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Regenerative Endodontics Procedures (REPs)

REPs was done for 10 mature maxillary necrotic teeth with periapical lesions. Instrumentation was done using Protaper Next system till size X3. Irrigation with 1.5 % NaOCl was done in the first visit. in the second visit, bleeding was induced in the canal by irritating the periapical area followed by the application of Biodentine as cervical plug then completion of the coronal restoration.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Necrotic Mature Maxillary anterior teeth with periapical lesions.

Exclusion Criteria

* Patients with mobile and fractured teeth
Minimum Eligible Age

20 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Alexandria University

OTHER

Sponsor Role lead

Responsible Party

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Noha Mohamed El Kateb

lecturer

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Alexandria University

Alexandria, , Egypt

Site Status

Countries

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Egypt

References

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Kateb NME, Fata MM. Influence of periapical lesion size on healing outcome following regenerative endodontic procedures: a clinical investigation. Oral Radiol. 2022 Oct;38(4):480-489. doi: 10.1007/s11282-021-00578-8. Epub 2021 Nov 26.

Reference Type DERIVED
PMID: 34826060 (View on PubMed)

Other Identifiers

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19832009

Identifier Type: -

Identifier Source: org_study_id