Dairy Based Probiotic Intervention and Cognitive, Emotional, and Inflammatory Outcomes

NCT ID: NCT04643080

Last Updated: 2020-11-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

47 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-03-07

Study Completion Date

2019-07-15

Brief Summary

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The purpose of this study was to determine the effect of dairy-based probiotics on cognitive function, emotional wellbeing, and inflammation. Subjects were assigned to either consume 6 oz of yogurt/day or abstain from consuming yogurt and other probiotic-containing foods for 12 weeks. Subjects completed baseline testing and 12-week follow-up testing consisting of a laboratory blood draw to assess inflammatory biomarkers, and a computerized assessment to evaluate cognitive and emotional wellbeing measures.

Detailed Description

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Conditions

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Cognitive Decline Cognitive Change Inflammation Emotions

Keywords

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Probiotics Cognition Emotional Wellbeing Inflammation Older Adults Yogurt

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Control

Subjects were asked to avoid consuming fermented foods for 12 weeks.

Group Type NO_INTERVENTION

No interventions assigned to this group

Yogurt

Subjects were asked to consume 6 oz. of yogurt daily for 12 weeks.

Group Type EXPERIMENTAL

Yogurt

Intervention Type OTHER

6 oz. of a commercially available yogurt were provided daily for 12 weeks

Interventions

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Yogurt

6 oz. of a commercially available yogurt were provided daily for 12 weeks

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* ability to participate in a 12-week study
* at least 50 years of age
* not currently taking a probiotic dietary supplement
* willing to refrain from consuming probiotic dietary supplements or fermented foods for 12-weeks
* willing to have blood drawn twice
* willing to consume yogurt daily for 12 weeks

Exclusion Criteria

\-
Minimum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Kansas State University

OTHER

Sponsor Role collaborator

University of Idaho

OTHER

Sponsor Role lead

Responsible Party

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Annie Roe

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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University of Idaho

Boise, Idaho, United States

Site Status

University of Idaho

Coeur d'Alene, Idaho, United States

Site Status

University of Idaho

Pocatello, Idaho, United States

Site Status

Kansas State University

Manhattan, Kansas, United States

Site Status

Countries

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United States

Other Identifiers

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18-203

Identifier Type: -

Identifier Source: org_study_id