Bimanual Motor Skill Learning Through Robotics in Chronic Cerebellar Stroke Survivors and Healthy Individuals
NCT ID: NCT04642599
Last Updated: 2024-12-16
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ACTIVE_NOT_RECRUITING
NA
50 participants
INTERVENTIONAL
2021-01-29
2028-12-31
Brief Summary
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Detailed Description
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They will practice several tasks on the robot REAplan® (bimanual version), requiring either movements with the affected arm (unimanual tasks) or complex, coordinated movements with both arms (bimanual tasks).
In addition, several "classical" clinical scales and tests will be used to evaluate overall motor-sensory-cognitive functions (clinical tests, questionnaires, ...).
Hand/digits motor function will be also evaluated with the kinetic device DexTrain®.
Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
BASIC_SCIENCE
NONE
Study Groups
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Chronic Cerebellar Stroke
Participants with a chronic cerebellar stroke
Bimanual motor skill learning with the REAplan® rehabilitation robot
REAplan® rehabilitation robot: training to perform complex, coordinated, bimanual movements
Healthy Individuals (Controls)
healthy participants
Bimanual motor skill learning with the REAplan® rehabilitation robot
REAplan® rehabilitation robot: training to perform complex, coordinated, bimanual movements
Interventions
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Bimanual motor skill learning with the REAplan® rehabilitation robot
REAplan® rehabilitation robot: training to perform complex, coordinated, bimanual movements
Eligibility Criteria
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Inclusion Criteria
* aged 18-90 years
* with a demonstrated stroke (ischemic or hemorrhagic) lesion on brain imaging
* 18-90 years
Exclusion Criteria
* drug/alcohol abuse
* severe aphasia / cognitive deficits interfering with study
* inability to voluntarily move the affected arm (i.e. complete paralysis of the arm)
* multiple strokes / dementia / psychiatric condition
HEALTHY INDIVIDUALS:
* neurological conditions interfering with the study
* drug/alcohol abuse
* pyschiatric condition
18 Years
90 Years
ALL
Yes
Sponsors
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Fonds National de la Recherche Scientifique
OTHER
Université Catholique de Louvain
OTHER
Louvain Bionics, UCLouvain
UNKNOWN
University Hospital of Mont-Godinne
OTHER
Responsible Party
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Pr Yves Vandermeeren, MD, PhD
Professor
Principal Investigators
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Yves Vandermeeren, MD, PhD
Role: PRINCIPAL_INVESTIGATOR
University Hospital of Mont-Godinne
Locations
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CHU UCL Namur, Mont-Godinne, Neurology Department, Stroke Unit
Yvoir, Namur, Belgium
Countries
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References
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Yeganeh Doost M, Orban de Xivry JJ, Bihin B, Vandermeeren Y. Two Processes in Early Bimanual Motor Skill Learning. Front Hum Neurosci. 2017 Dec 20;11:618. doi: 10.3389/fnhum.2017.00618. eCollection 2017.
Dehem S, Gilliaux M, Lejeune T, Delaunois E, Mbonda P, Vandermeeren Y, Detrembleur C, Stoquart G. Effectiveness of a single session of dual-transcranial direct current stimulation in combination with upper limb robotic-assisted rehabilitation in chronic stroke patients: a randomized, double-blind, cross-over study. Int J Rehabil Res. 2018 Jun;41(2):138-145. doi: 10.1097/MRR.0000000000000274.
Doost MY, Orban de Xivry JJ, Herman B, Vanthournhout L, Riga A, Bihin B, Jamart J, Laloux P, Raymackers JM, Vandermeeren Y. Learning a Bimanual Cooperative Skill in Chronic Stroke Under Noninvasive Brain Stimulation: A Randomized Controlled Trial. Neurorehabil Neural Repair. 2019 Jun;33(6):486-498. doi: 10.1177/1545968319847963. Epub 2019 May 15.
Gathy E, Cadiat N, Gerardin E, Lambert J, Herman B, Leeuwerck M, Bihin B, Vandermeeren Y. Bimanual coordinated motor skill learning in patients with a chronic cerebellar stroke. Exp Brain Res. 2024 Jun;242(6):1517-1531. doi: 10.1007/s00221-024-06830-x. Epub 2024 May 9.
Other Identifiers
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BimMSkL-Cerebellum
Identifier Type: -
Identifier Source: org_study_id