Prevalence of Musculoskeletal Symptoms in the Cambridge NIHR BioResource

NCT ID: NCT04632563

Last Updated: 2020-11-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

5000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-11-30

Study Completion Date

2021-08-31

Brief Summary

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Musculoskeletal diseases, such as osteoarthritis, represent a large proportion of the global burden of disease with hip and knee osteoarthritis alone being the 11th greatest cause of disease burden.

The purpose of this study is to determine the level of musculoskeletal symptoms in members of the Cambridge National Institute for Health Research (NIHR) BioResource and see if this is associated with their possession of genetic markers that have been identified as being associated with osteoarthritis.

This will allow us to determine the real level of musculoskeletal symptoms in this large cohort of volunteers and provide basic information that could be used to facilitate further musculoskeletal research in the NIHR BioResource population.

Detailed Description

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All active members of the Cambridge NIHR BioResource will be approached.

They will be sent an email outlining the purpose of the study and asking that if they would like to take part to please complete the online questionnaire which will be linked to in the email.

For those individuals who agree to participate and complete the questionnaire, the Cambridge NIHR BioResource will provide the genetic marker information it already holds for specific markers that are known to be associated with osteoarthritis.

Conditions

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Musculoskeletal Diseases Musculoskeletal Injury

Study Design

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Observational Model Type

OTHER

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Member of BioResource

Any BioResource member who consents to take part in the study and completes the study questionnaire.

Questionnaire including MSK-HQ (Musculoskeletal Health Questionnaire)

Intervention Type OTHER

A questionnaire regarding musculoskeletal past medical history and current symptoms.

Interventions

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Questionnaire including MSK-HQ (Musculoskeletal Health Questionnaire)

A questionnaire regarding musculoskeletal past medical history and current symptoms.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Member of the NIHR BioResource
* Willing to consent to participate

Exclusion Criteria

* Previous self-report of osteoarthritis on joining BioResource
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Cambridge

OTHER

Sponsor Role collaborator

Cambridge University Hospitals NHS Foundation Trust

OTHER

Sponsor Role lead

Responsible Party

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Professor Andrew McCaskie

Professor of Orthopaedic Surgery / Head of Department

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Andrew McCaskie

Role: PRINCIPAL_INVESTIGATOR

University of Cambridge

Central Contacts

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Benjamin Davies

Role: CONTACT

Phone: +44 1223 217551

Email: [email protected]

Other Identifiers

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A095310

Identifier Type: -

Identifier Source: org_study_id