The OsteoStrand Plus Deformity Study

NCT ID: NCT04629794

Last Updated: 2023-04-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

28 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-03-05

Study Completion Date

2024-06-30

Brief Summary

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A clinical study evaluating outcomes for patients with spinal deformity.

Detailed Description

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A clinical study evaluating deformity patients treated with Demineralized Bone Matrix as compared to patients treated with Bone Morphogenetic Protein.

Conditions

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Spinal Fusion

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Demineralized Bone Matrix

Prospective cohort subjects undergoing deformity correction surgery that receive Demineralized Bone Matrix (DBM).

Group Type ACTIVE_COMPARATOR

Posterolateral Lumbar Fusion with Demineralized Bone Fibers

Intervention Type PROCEDURE

Posterolateral Lumbar Fusion with Demimeralized Bone Fibers

Bone Morphogenic Protein

Retrospective cohort subjects that underwent deformity correction surgery and received Bone Morphogenic Protein (BMP).

Group Type ACTIVE_COMPARATOR

Posterolateral Lumbar Fusion with Bone Morphogenic Protein

Intervention Type PROCEDURE

Posterolateral Lumbar Fusion with Bone Morphogenic Protein

Interventions

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Posterolateral Lumbar Fusion with Demineralized Bone Fibers

Posterolateral Lumbar Fusion with Demimeralized Bone Fibers

Intervention Type PROCEDURE

Posterolateral Lumbar Fusion with Bone Morphogenic Protein

Posterolateral Lumbar Fusion with Bone Morphogenic Protein

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

-≥18 years of age

* Indicated for deformity correction surgery
* Require spinal fusion at four or more levels
* Are willing to return for follow-up visits
* Willing to sign the Informed Consent Forms

Exclusion Criteria

* Uncontrolled diabetes
* Morbid obesity
* history of alcohol or drug abuse
* Corticosteroid use
* Fever or leukocytosis
* Systemic infection
* Active malignancy
* Elevation of white blood cell count
* Osteoporosis
* Disease of bone metabolism
* Unsuitable or insufficient bone support
* Skeletal immaturity
* Prior fusion
* Use of steroids, immune suppressants, osteoporosis medications
* Use of internal bone stimulators
* Institutionalized or a prisoner
* Undergoing (Undergone) a worker's compensation case
* Pregnancy (includes women who are currently pregnant, lactating or wishing to become pregnant during the study duration)
* Participation in another research study involving another implant, product or drug that may affect the outcomes of this clinical study within the last 30 days, or planned during this clinical study
* Any other condition that the Investigator determines is unacceptable for enrollment into this clinical study
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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SeaSpine, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Michael Chang, MD

Role: PRINCIPAL_INVESTIGATOR

Sonoran Spine

Locations

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Sonoran Spine

Tempe, Arizona, United States

Site Status

Countries

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United States

Other Identifiers

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SS-OS-1802

Identifier Type: -

Identifier Source: org_study_id

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