Mobile Application to Assist Adherence to Oral Anticancer Agents and Symptom Management

NCT ID: NCT04626830

Last Updated: 2020-11-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

77 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-06-25

Study Completion Date

2019-12-01

Brief Summary

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The use of oral anticancer agents (OAAs) in cancer treatment has increased especially in the last two decades. The use of mobile health technologies in the management of OAA can be beneficial in terms of treatment adherence and symptom management.The aim of this study is to explore how a Smartphone mobile application can help improve the cancer treatment process in people who are used oral anticancer agents. This study will be done a randomized-controlled trial to test the intervention.

Detailed Description

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Background: The use of mobile health technologies in the management of OAA can be beneficial in terms of treatment adherence and symptom management.

Objective/Hipothesis: The purpose of this study is to explore the effectiveness of a mobile application on treatment adherence and symptom management in patients using OAA. The following hypotheses (H) will teste in this study:

H0a: A mobile application developed for patients using OAA has not increased treatment adherence.

H1a: A mobile application developed for patients using OAA has increased treatment adherence.

H0b: A mobile application developed for patients using OAA has not decreased the frequency and severity of symptoms.

H1b: A mobile application developed for patients using OAA has decreased the frequency and severity of symptoms.

Study Design: The investigators will recruit and randomly assign 100 patients from the two cancer care sites who have recently been prescribed oral anticancer agents to receive either the mobile app intervention or standard care. Participants will be stratified by age and anticancer treatment ( i.e. simple and complex) regimen. Patients will be follow 6 months. Medication adherence, symptom severity will serve as primary outcomes.

Conditions

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Cancer Adherence to Medication Regime Symptom Management

Keywords

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Cancer Mobile applications Oral anticancer agents Oral Chemotherapy Medication adherence Nursing

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

SINGLE

Investigators

Study Groups

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Mobile Application Intervention

Participants in the intervention group will receive 6 months the mobile application (OKTED) for improving symptoms and adherence to oral anticancer agents. The mobile application will consist of three modules. The first module will include OAA-specific information, a calendar in which start/end dates can be record, and a medication reminder. The second module will include information about common and urgent symptoms and recommendations for the management of these symptoms. The last module will comprise a question and answer section.

Group Type EXPERIMENTAL

Mobile Application Intervention

Intervention Type OTHER

Participants appointed to the intervention group will receive the mobile application intervention for six months after enrollment. The mobile app (OKTED) intervention will consist of completing responding to weekly assessments regarding symptoms, side effects, and medication adherence, as well as receiving personalized feedback about responses.

Standard Care

Participants in the control group will receive standard oncology care only.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Mobile Application Intervention

Participants appointed to the intervention group will receive the mobile application intervention for six months after enrollment. The mobile app (OKTED) intervention will consist of completing responding to weekly assessments regarding symptoms, side effects, and medication adherence, as well as receiving personalized feedback about responses.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Using OAAs for cancer treatment and taking at least one cure
* Taking OAAs for at least six months
* Knowing the diagnosis
* Communicating verbally
* Scoring less than three on the Eastern Cooperative Oncology Group (ECOG) scale
* Having a smartphone with IOS or Android software
* Actively using the smartphone
* Consenting to download the mobile application on one's mobile phone
* Volunteering to participate in the research.

Exclusion Criteria

* Participation in a similar study aimed at increasing treatment adherence
* Having physical, cognitive, or memory-related problems that significantly impair one's daily activities
* Having a smartphone with Windows or Blackberry software.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Koç University

OTHER

Sponsor Role collaborator

Gazi University

OTHER

Sponsor Role collaborator

Baskent University

OTHER

Sponsor Role lead

Responsible Party

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Akile Karaaslan Eşer

Assistant professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Başkent University

Ankara, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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Karaaslan-Eser A, Ayaz-Alkaya S. The effect of a mobile application on treatment adherence and symptom management in patients using oral anticancer agents: A randomized controlled trial. Eur J Oncol Nurs. 2021 Jun;52:101969. doi: 10.1016/j.ejon.2021.101969. Epub 2021 May 4.

Reference Type DERIVED
PMID: 33991868 (View on PubMed)

Other Identifiers

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Project No: 2018.1.18.

Identifier Type: -

Identifier Source: org_study_id