Neurocognitive Functions of Recovered COVID-19 Patients

NCT ID: NCT04622748

Last Updated: 2020-11-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Total Enrollment

160 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-07-10

Study Completion Date

2020-12-10

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This study is carried on in Wuchang Hospital in Wuhan, China. The investigators plan to recruit 80 patients with COVID-19 and 80 matched healthy control. Using the design of case-control study, the study aims to assess the neurocognitive functions such as executive function and attentional bias in recovered patients with COVID-19 under normal and stress conditions, and to analyze the influencing factors of neurocognitive functions, such as mental health conditions, inflammation indicators and cardiopulmonary function.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Cognition Covid-19

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

COVID-19

Recovered COVID-19 patients in Wuhan

Trier Social Stress Test

Intervention Type BEHAVIORAL

8-min oral calculation and 5-min speech

Healthy Control

Uninfected people in Wuhan

Trier Social Stress Test

Intervention Type BEHAVIORAL

8-min oral calculation and 5-min speech

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Trier Social Stress Test

8-min oral calculation and 5-min speech

Intervention Type BEHAVIORAL

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Recovered COVID-19 patients or uninfected residents in Wuhan, with an education level above elementary school and are able to complete cognitive tasks;
* Willing to participate in this study and sign informed consent.

Exclusion Criteria

* Subjects with body temperature\> 38°C;
* Subjects who are in menstruation and pregnancy;
* Subjects suffering from cardiopulmonary diseases before the new coronary pneumonia epidemic (such as heart disease, pulmonary hypertension, congestive heart failure, etc.);
* Subjects with severe disturbances in consciousness, cognitive dysfunction, mental disorders, visual and hearing disorders, bone and joint diseases, etc.;
* Subjects with abnormal immune system and severe organ dysfunction (heart, liver, kidney, etc.);
* Subjects who are unwilling to participate in this study and cannot complete all surveys and cognitive function tests.
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Peking University Sixth Hospital

OTHER

Sponsor Role collaborator

Wuhan Wuchang Hospital

UNKNOWN

Sponsor Role collaborator

National Institute on Drug Dependence, China

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Lin Lu, Dr.

Role: STUDY_DIRECTOR

National Institute on Drug Dependence, Peking University

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Wuhan Wuchang Hospital

Wuhan, Hubei, China

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

China

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Ping Wu, Dr.

Role: CONTACT

Phone: 861082802470

Email: [email protected]

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Guofu Huang, Dr

Role: primary

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

NIDD-2020-Neurocognition

Identifier Type: -

Identifier Source: org_study_id