An Outpatient Study Investigating Non-prescription Treatments for COVID-19
NCT ID: NCT04621149
Last Updated: 2022-09-30
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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TERMINATED
PHASE2
10 participants
INTERVENTIONAL
2020-11-15
2022-03-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
FACTORIAL
TREATMENT
QUADRUPLE
Study Groups
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placebo
1 liter of filtered water
placebo
filtered water
chlorine dioxide aqueous solution (AS)
1 liter of filtered water with AS
chlorine dioxide
chlorine dioxide is an antimicrobial agent used for a variety of purposes including as a water purification product, a disinfectant on food, etc.
placebo with zinc acetate (ZA)
1 liter of filtered water with ZA
zinc acetate
zinc acetate lozenges have been suggested to have antiviral properties
placebo
filtered water
AS with ZA
1 liter of filtered water with AS and ZA
chlorine dioxide
chlorine dioxide is an antimicrobial agent used for a variety of purposes including as a water purification product, a disinfectant on food, etc.
zinc acetate
zinc acetate lozenges have been suggested to have antiviral properties
placebo with famotidine, lactoferrin and green tea extract (FLG)
1 liter of filtered water with FLG
Famotidine
famoitidine is a histamine-2 blocker sold over the counter to reduce stomach acid
placebo
filtered water
lactoferrin, green tea extract
lactoferrin and green tea extract are dietary supplements
AS with FLG
1 liter of filtered water with AS and FLG
chlorine dioxide
chlorine dioxide is an antimicrobial agent used for a variety of purposes including as a water purification product, a disinfectant on food, etc.
Famotidine
famoitidine is a histamine-2 blocker sold over the counter to reduce stomach acid
lactoferrin, green tea extract
lactoferrin and green tea extract are dietary supplements
placebo with ZA and FLG
1 liter of filtered water with ZA and FLG
zinc acetate
zinc acetate lozenges have been suggested to have antiviral properties
Famotidine
famoitidine is a histamine-2 blocker sold over the counter to reduce stomach acid
placebo
filtered water
lactoferrin, green tea extract
lactoferrin and green tea extract are dietary supplements
AS with ZA and FLG
1 liter of filtered water with AS, ZA, and FLG
chlorine dioxide
chlorine dioxide is an antimicrobial agent used for a variety of purposes including as a water purification product, a disinfectant on food, etc.
zinc acetate
zinc acetate lozenges have been suggested to have antiviral properties
Famotidine
famoitidine is a histamine-2 blocker sold over the counter to reduce stomach acid
lactoferrin, green tea extract
lactoferrin and green tea extract are dietary supplements
Interventions
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chlorine dioxide
chlorine dioxide is an antimicrobial agent used for a variety of purposes including as a water purification product, a disinfectant on food, etc.
zinc acetate
zinc acetate lozenges have been suggested to have antiviral properties
Famotidine
famoitidine is a histamine-2 blocker sold over the counter to reduce stomach acid
placebo
filtered water
lactoferrin, green tea extract
lactoferrin and green tea extract are dietary supplements
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
2. Stated willingness to comply with all study procedures and availability for the duration of the study
3. Male or female, aged 20-70
4. Confirmed diagnosis of COVID-19 by positive COVID-19 test. Symptoms of a mild degree such that hospitalization is not required. Within 7 days of symptom onset.
5. Ability to drink at least 1 liter of water daily and be willing to adhere to the study regimen
Exclusion Criteria
2. Pregnancy or lactation
3. Diagnosis of diabetes mellitus
4. currently taking paroxetine or digoxin
5. Individuals with diabetes mellitus
20 Years
70 Years
ALL
No
Sponsors
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Profact, Inc.
OTHER
Responsible Party
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Principal Investigators
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Jonathan Murphy, MD, MD(H)
Role: PRINCIPAL_INVESTIGATOR
Profact, Inc.
Locations
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AZ Good Health Center
Tempe, Arizona, United States
Countries
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References
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Kreuzberger N, Hirsch C, Chai KL, Tomlinson E, Khosravi Z, Popp M, Neidhardt M, Piechotta V, Salomon S, Valk SJ, Monsef I, Schmaderer C, Wood EM, So-Osman C, Roberts DJ, McQuilten Z, Estcourt LJ, Skoetz N. SARS-CoV-2-neutralising monoclonal antibodies for treatment of COVID-19. Cochrane Database Syst Rev. 2021 Sep 2;9(9):CD013825. doi: 10.1002/14651858.CD013825.pub2.
Other Identifiers
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Profact-01
Identifier Type: -
Identifier Source: org_study_id
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