Causes of Health Disparities in African Americans With Coronary Artery Disease on Clopidogrel

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Study Classification

OBSERVATIONAL

Study Start Date

2021-03-19

Study Completion Date

2021-03-19

Brief Summary

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African Americans with coronary artery disease who have been prescribed clopidogrel (also known as Plavix), an antiplatelet drug will be enrolled. The purpose of this study is to help identify why African Americans are at an increased risk of having a major heart attack or stroke after a common procedure to open up blocked arteries with stents. The knowledge to be gained from this study includes:

1. A better understanding of the metabolism of the antiplatelet drug, clopidogrel, and abnormal platelet function in African Americans; this understanding may provide a basis for potential future therapy
2. A better understanding of challenges to taking clopidogrel as prescribed by a doctor and opinions about a genetic test related to this medicine.

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Detailed Description

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Conditions

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Coronary Artery Disease

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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African Americans with Coronary Artery Disease

African Americans with Coronary Artery Disease and currently taking clopidogrel

CORONARY ARTERY DISEASE AND CLOPIDOGREL: PATIENT SURVEY

Intervention Type BEHAVIORAL

Survey is a non-standardized assessment of demographics, medication compliance and reasons for non- compliance.

Interventions

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CORONARY ARTERY DISEASE AND CLOPIDOGREL: PATIENT SURVEY

Survey is a non-standardized assessment of demographics, medication compliance and reasons for non- compliance.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

1. 18 years of age or older
2. Sex: Male and Female
3. Race: Self-identified as African American
4. History of percutaneous coronary intervention in the past 12 months
5. Currently taking aspirin and clopidogrel for at least one month and up to one year
6. English speaking