Fast Reversal of Warfarin and Early Surgery in Patients With Trochanteric Hip Fracture A Case-control Study
NCT ID: NCT04614090
Last Updated: 2020-11-03
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
198 participants
OBSERVATIONAL
2017-10-01
2018-06-26
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
RETROSPECTIVE
Study Groups
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99 warfarin patients
warfarin patients were operated within 24 h with a cephalomedullary nail due to a trochanteric or subtrochanteric hip fracture. All patients on warfarin were reversed if necessary to INR≤1.5 before surgery using vitamin K and/or four-factor prothrombin complex concentrate (PCC)
No interventions assigned to this group
99 patients without anticoagulants
As a 1:1 ratio control group matched for age, gender and surgical implant. All patients were operated within 24 h with a cephalomedullary nail due to a trochanteric or subtrochanteric hip fracture.
No interventions assigned to this group
Eligibility Criteria
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Exclusion Criteria
* Late presentation to the hospital
* Other injuries
60 Years
ALL
No
Sponsors
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Stockholm South General Hospital
OTHER
Karolinska Institutet
OTHER
Responsible Party
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Leif Mattisson
Senior Consultant Orthopaedic Surgeon MD.,Ph.D.
Principal Investigators
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Leif Mattisson
Role: PRINCIPAL_INVESTIGATOR
Stockholm South General Hospital
Locations
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Södersjukhuset
Stockholm, Sjukhusbacken 10, Sweden
Countries
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References
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Mattisson L, Lapidus LJ, Enocson A. Is fast reversal and early surgery (within 24 h) in patients on warfarin medication with trochanteric hip fractures safe? A case-control study. BMC Musculoskelet Disord. 2018 Jun 26;19(1):203. doi: 10.1186/s12891-018-2126-3.
Other Identifiers
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Leif Mattisson
Identifier Type: -
Identifier Source: org_study_id